Receptor protein serine/threonine kinases (EC 2.7.11.30) are enzyme-linked receptors that belong to protein-serine/threonine kinases. The systematic name of this enzyme class is ATP:[receptor-protein] phosphotransferase. Proteins from this group participate in numerous biological pathways, processes and diseases including MAPK signaling pathway, cytokine-cytokine receptor interactions, TGF beta signaling pathway, colorectal cancer, pancreatic cancer, and chronic myeloid leukemia.
Receptor serine/threonine kinases directly phosphorylate specific serines or threonines on themselves and on other regulatory proteins.
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References
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