The following is a list of independent pharmaceutical, biotechnology and medical companies listed on a stock exchange (as indicated) that have generated a revenue of at least US$10 billion, ranked by their revenue in the respective financial year.

It does not include biotechnology companies that are now owned by, or form a part of, larger pharmaceutical groups.

Ranking by revenue

The following table lists the largest biotechnology and pharmaceutical companies ranked by revenue in billion USD. The change column indicates the company's relative position in this list compared to its relative position in the preceding year; i.e., an increase would be moving closer to rank 1 and vice versa. Green cells indicate years where revenue increased compared to the preceding year. Red cells indicate those years when there has been a decrease.

Largest biotechnology and pharmaceutical companies ranked by revenue in billion USD.
Rank Chg Company Country Traded on 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016
1SteadyJohnson & Johnson  USANYSE: JNJ 94.19[1] 88.82[2] 85.16[3] 79.99[3] 93.78[4] 82.59[4] 82.06[5] 81.60[6] 76.50[7] 71.89[8]
2SteadySinopharm  CHNSEHK: 1099 81.31[9] 83.64[10] 84.06[11] 80.19[12] 75.68[12] 71.75[13] 60.18[14] 48.75[15] 43.63[16] 36.56[17]
3SteadyRoche  SUISIX: ROG 80.31[18] 66.42[19] 68.48[20] 69.77[21] 67.83[22] 62.99[22] 63.85[23] 56.86[24] 57.37[25] 50.11[26]
4Increase 7Eli Lilly & Co  USANYSE: LLY 65.18[27] 45.03[28] 34.12[29] 28.54[30] 28.32[31] 24.54[32] 22.32[33] 21.49[34] 22.90[35] 21.22[36]
5Decrease 1Merck & Co.  USANYSE: MRK 65.01[37] 64.17[38] 60.12[39] 59.28[40] 48.70[41] 41.52[41] 46.84[42] 42.30[43] 40.10[44] 39.80[45]
6Decrease 1Pfizer  USANYSE: PFE 62.58[46] 63.63[47] 59.55[47] 100.33[48] 81.29[49] 41.91[50] 41.17[50] 40.83[50] 52.54[51] 52.82[52]
7Decrease 1AbbVie  USANYSE: ABBV 61.16[53] 56.33[54] 54.32[55] 58.05[56] 56.20[57] 45.80[57] 33.27[58] 32.75[59] 28.22[60] 25.56[61]
8Decrease 1AstraZeneca  GBR
 SWE		LSE: AZN 58.74[62] 54.07[63] 45.81[64] 44.35[65] 37.42[66] 26.62[67] 24.38[68] 22.09[69] 22.47[70] 23.00[71]
9SteadyNovartis  SUINYSE: NVS 54.53[72] 50.32[73] 45.44[74] 50.55[75] 51.63[76] 48.66[76] 47.45[77] 44.75[78] 49.11[79] 48.52[80]
10Increase 2Sanofi  FRANYSE: SNY 52.15[81] 42.68[82] 46.84[83] 46.86[84] 43.24[85] 41.27[86] 39.28[87] 39.07[88] 42.91[89] 36.57[90]
11Decrease 3Bayer  GERFWB: BAYN 49.56[91] 51.07[92] 51.72[93] 53.88[94] 49.46[95] 47.40[96] 48.02[97] 45.06[98] 37.94[99] 25.27[100]
12Increase 2Novo Nordisk  DENNYSE: NVO 48.86[101] 40.52[102] 33.83[103] 25.46[104] 21.66[105] 19.52[105] 18.30[106] 6.99[107] 18.77[108] 16.61[109]
13Decrease 3Bristol Myers Squibb  USANasdaq: BMY 48.19[110] 48.30[111] 45.01[112] 46.16[113] 46.39[114] 42.52[114] 26.15[115] 22.56[116] 20.80[117] 19.43[118]
14Increase 1GlaxoSmithKline  GBRLSE: GSK 44.59[119] 39.28[120] 38.63[121] 36.14[122] 46.91[123] 46.17[124] 43.92[125] 43.14[126] 42.05[127] 34.79[128]
15Decrease 2Abbott Laboratories  USANasdaq: ABT 44.33[129] 41.95[130] 40.11[131] 43.65[132] 43.08[133] 34.61[134] 31.90[135] 30.60[136] 27.39[137] 20.85[138]
16SteadyShanghai Pharmaceuticals  CHNSSE: 601607 39.40[139] 38.65[140] 36.68[141] 32.33[142] 31.82[143] 29.29[143] 27.50[143] 23.45[143] 19.28[143] 17.80[144]
17SteadyAmgen  USANasdaq: AMGN 36.75[145] 33.42[146] 28.19[147] 26.32[148] 25.98[149] 25.42[150] 23.40[151] 23.70[152] 22.80[153] 22.99[154]
18SteadyBoehringer Ingelheim  GERPrivate 29.37[155] 27.70[156] 25.90[157] 22.50[158] 22.40[159] 21.75[160] 21.67[161] 17.54[162] 16.41[162]
19SteadyTakeda Pharmaceutical  JPNTYO: 4502 29.31[163] 30.24[164] 30.34[165] 29.31[166] 27.76[167] 31.17[168] 19.10[169] 16.70[170] 15.96[171]
20SteadyGilead Sciences  USANasdaq: GILD 29.44[172] 28.75[173] 27.12[174] 27.28[175] 27.31[175] 24.69[176] 22.45[177] 22.13[178] 25.70[179] 30.39[179]
21SteadySiemens Healthineers  GERFWB: SHL 23.21[180] 23.32[181] 23.09[182] 20.61[183] 16.56[183] 16.62[184] 15.37[185] 16.56[186] 14.25[186]
22SteadyMerck Group  GERETR: MRK 23.18[187] 22.79[188] 23.64[189] 21.40[190] 20.08[191] 18.25[192] 16.48[193] 18.70[194] 16.62[195]
23SteadyJointown Pharmaceutical  CHNSSE: 600998 21.32[196] 21.15[197] 19.81[198] 18.04[199] 16.34[200] 14.67[201] 12.85[202] 10.90[203] 9.07[204]
24SteadyGE Healthcare  USANasdaq: GEHC 20.63[205] 19.67[206] 19.55[207] 18.34[208] 17.73[209] 18.01[210] 19.94[211] 19.78[211] 19.02[211] 18.21[211]
25SteadyTeva Pharmaceuticals  ISRNasdaq: TEVA 17.26[212] 16.54[213] 15.85[214] 14.93[215] 15.88[216] 16.66[217] 16.89[218] 18.90[219] 22.40[220] 21.90[221]
26SteadyOtsuka Holdings  JPNTYO: 4578 15.78[222] 14.23[223] 13.05[224] 11.65[225] 11.06[225] 10.85[225] 10.04[225] 9.64[225] 9.29[225]
27SteadyKenvue  USANYSE: KVUE 15.12[226] 15.46[227] 15.44[228] 14.95[228]
28Increase 2Haleon  GBRLSE: HLN 15.01[229] 14.15[230] 14.29[231] 13.14[232] 11.77[233]
29SteadyRegeneron Pharmaceuticals  USANasdaq: REGN 14.34[234] 14.20[235] 13.12[236] 12.17[237] 16.07[238] 8.50[238] 7.86[239] 6.71[239] 5.87[239] 4.86[240]
30Decrease 2Viatris  USANasdaq: VTRS 14.30[241] 14.69[242] 15.43[243] 16.22[244] 17.81[244] 11.95[245]
31SteadyAstellas Pharma  JPNTYO: 4503 12.68[246] 10.54[247] 10.87[248] 10.08[249] 10.85[250] 11.29[250] 12.27[251] 12.07 12.63
32SteadyDaiichi Sankyo  JPNTYO: 4568 12.51[252] 10.52[253] 8.40[254] 6.87[255] 6.33[256] 6.45[257] 6.11[258] 6.31[259] 6.28[260]
33SteadyVertex Pharmaceuticals  USANasdaq: VRTX 12.00[261] 11.02[262] 9.87[263] 8.93[264] 7.57[265] 6.20[266] 4.16[267] 3.04[268] 2.16[269] 1.68[270]
34SteadyBaxter International  USANYSE: BAX 11.24[271] 10.64[272] 14.81[273] 15.11[274] 12.78[275] 11.63[276] 11.36[276] 11.13[277] 10.56[277] 10.16[278]

See also

References

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  215. ↑ "Teva Reports Fourth Quarter and Full Year 2022 Financial Results".
  216. ↑ "Teva Reports Fourth Quarter and Full Year 2021 Financial Results" (PDF). Tel Aviv: Teva. 9 February 2022. Retrieved 2022-09-26.
  217. ↑ TEVA
  218. ↑ "Teva Reports Fourth Quarter and Full Year 2019 Financial Results".
  219. ↑ TEVA
  220. ↑ "Teva Reports 2017 Full Year and Fourth Quarter Financial Results". 8 February 2018.
  221. ↑ "Teva Reports Full Year and Fourth Quarter 2016 Financial Results". Archived from the original on 2018-02-03. Retrieved 2018-02-08.
  222. ↑ "Consolidated Financial Results for the Fiscal Year Ended December 31, 2024" (PDF). Otsuka Holdings.
  223. ↑ "Integrated Report 2024" (PDF). Otsuka Holdings.
  224. ↑ "Consolidated Financial Results for the Fiscal Year Ended December 31, 2022" (PDF). Otsuka Holdings.
  225. 1 2 3 4 5 6 "Otsuka Integrated Report 2021" (PDF).
  226. ↑ "Kenvue Annual Rport 2025" (PDF).
  227. ↑ "Kenvue Reports Full Year and Fourth Quarter 2024 Results".
  228. 1 2 "Kenvue Reports Full Year and Fourth Quarter 2023 Results".
  229. ↑ "Haleon Annual Report and Form 20-F 2025" (PDF).
  230. ↑ "Haleon 2024 Full year results" (PDF).
  231. ↑ "Haleon 2023 Full Year Results" (PDF).
  232. ↑ "Haleon 2022 Full Year Results" (PDF).
  233. ↑ "Haleon Prospetus" (PDF).
  234. ↑ "Regeneron Reports Fourth Quarter and Full Year 2025 Financial and Operating Results".
  235. ↑ "Regeneron Reports Fourth Quarter and Full Year 2024 Financial and Operating Results".
  236. ↑ "Regeneron Reports Fourth Quarter and Full Year 2023 Financial and Operating Results".
  237. ↑ "Regeneron Reports Fourth Quarter and Full Year 2022 Financial and Operating Results".
  238. 1 2 Regeneron Reports Fourth Quarter and Full Year 2021 Financial and Operating Results (Report). Regeneron. 4 February 2022.
  239. 1 2 3 "Regeneron Form 10-K 2019".
  240. ↑ "Regeneron Form 10-K 2016".
  241. ↑ "Viatris Reports Fourth-Quarter and Full-Year 2025 Financial Results".
  242. ↑ "Viatris Reports Fourth Quarter and Full Year 2024 Financial Results".
  243. ↑ "Viatris Reports Fourth-Quarter and Full-Year 2023 Financial Results".
  244. 1 2 "Viatris Reports Strong Fourth Quarter and Full Year 2022 Financial Results and Provides 2023 Financial Guidance".
  245. ↑ "Viatris Reports Strong Fourth Quarter and Full-Year 2021 Financial Results".
  246. ↑ "Financial Results of Astellas for Fiscal Year 2024" (PDF).
  247. ↑ "Financial Results of Astellas for Fiscal Year 2023" (PDF).
  248. ↑ "Financial Results of Astellas for Fiscal Year 2022" (PDF).
  249. ↑ "Financial Results of Astellas for Fiscal Year 2021" (PDF).
  250. 1 2 For the Year Ended March 31, 2021 Annual Report 2021 (PDF) (Report). Astellas. 31 March 2020.
  251. ↑ "Astellas Pharma Inc. Annual Report 2018" (PDF). www.astellas.com.
  252. ↑ "Daiichi Sankyo FY2024 Financial Results" (PDF).
  253. ↑ "Daiichi Sankyo FY2023 Financial Results" (PDF).
  254. ↑ "Daiichi Sankyo FY2022 Financial Results" (PDF).
  255. ↑ "Daiichi Sankyo FY2021 Financial Results" (PDF).
  256. ↑ "Daiichi Sankyo FY2020 Financial Results" (PDF).
  257. ↑ "Daiichi Sankyo FY2019 Financial Results" (PDF).
  258. ↑ "Daiichi Sankyo FY2018 Financial Results" (PDF).
  259. ↑ "Daiichi Sankyo FY2017 Financial Results" (PDF).
  260. ↑ "Daiichi Sankyo FY2016 Financial Results" (PDF).
  261. ↑ "Vertex Reports Fourth Quarter and Full Year 2025 Financial Results".
  262. ↑ "Vertex Reports Fourth Quarter and Full Year 2024 Financial Results".
  263. ↑ "Vertex Reports Fourth Quarter and Full Year 2023 Financial Results".
  264. ↑ "Vertex Reports Fourth Quarter and Full Year 2022 Financial Results".
  265. ↑ "Vertex Reports Fourth Quarter 2021 and Full Year Financial Results".
  266. ↑ "Vertex Reports Full-Year and Fourth-Quarter 2020 Financial Results".
  267. ↑ "Vertex Reports Full-Year and Fourth-Quarter 2019 Financial Results".
  268. ↑ "Vertex Reports Full-Year and Fourth-Quarter 2018 Financial Results".
  269. ↑ "Vertex Reports Full-Year and Fourth-Quarter 2017 Financial Results".
  270. ↑ "Vertex Reports Full-Year and Fourth-Quarter 2016 Financial Results".
  271. ↑ "Baxter Reports Fourth-Quarter 2025 Results".
  272. ↑ "Baxter Reports Fourth-Quarter and Full-Year 2024 Results".
  273. ↑ "Baxter Reports Fourth-Quarter and Full-Year 2023 Results".
  274. ↑ "Baxter Reports Fourth-Quarter and Full-Year 2022 Results".
  275. ↑ "Baxter Reports Fourth-Quarter and Full-Year 2021 Results".
  276. 1 2 Statements of Income (Unaudited) Baxter International
  277. 1 2 Statements of Income (Unaudited) Baxter International
  278. ↑ Statements of Income (Unaudited) Baxter International
allikas: https://en.wikipedia.org/wiki/List_of_largest_biomedical_companies_by_revenue