Not to be confused with Methapyrilene.

Methaphenilene is an antihistamine and anticholinergic.

Synthesis

Methaphenilene can be synthesized from N,N-dimethyl-N′-phenylethane-1,2-diamine by alkylation with 2-(chloromethyl)thiophene.[1]

Methaphenilene synthesis

See also

References

  1. ^ Leonard F, Solmssen UV (June 1948). "Thenyl Substituted Diamines with Antihistaminic Activity". Journal of the American Chemical Society. 70 (6): 2064–7. doi:10.1021/ja01186a023. PMID 18863797.


Allikas: https://en.wikipedia.org/wiki/Methaphenilene
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