The 1910 Isle of Man Tourist Trophy races took place on the Short Course (St John's, Ballacraine, Kirk Michael, Peel, St John's).

Thursday 26 May 1910 – 10 laps (158+1⁄8 miles (254.5 km)) St John's Short Course.^[1]

The 4th International Auto-cycle Tourist Trophy[2]

Pos # Rider Bike Cyl. 500 Single & 750 Twin Open Class race classification Laps Time Speed Prizes & remarks 1 14 Charlie Collier 5 hp (3.7 kW) Matchless 666cc 2 10 3:07.54 50.59 mph 1st Prize - Trophy and £40 2 1 Harry Collier 5 hp (3.7 kW) Matchless 666cc 2 10 3:12.45 49.29 mph 2nd Prize - £20. 3 9 Walter Creyton 3+2⁄3 hp (2.7 kW) Triumph 499cc 1 10 3:17.58 48.02 mph 3rd Prize - £10 4 37 Jack Adamson 3+2⁄3 hp (2.7 kW) Triumph 499cc 1 10 3:21.47 47.09 mph Silver Cup and £5 5s for the 1st Private owners' machine. 5 36 Jack Scriven 4 hp (3.0 kW) Rex 660cc 2 10 3:23.35 44.66 mph Silver Cup and £2 2s for the 2nd Private owners' machine. 6 7 Jack Marshall 3+2⁄3 hp (2.7 kW) Triumph 499cc 1 10 3:24.47 46.40 mph 7 34 Howard Lister-Cooper 3+2⁄3 hp (2.7 kW) Triumph 1 10 3:25.24 46.23 mph 8 8 Billy Newsome 3+2⁄3 hp (2.7 kW) Triumph 499cc 1 10 3:26.35 45.98 mph 9 31 Frank Philipp 5 hp (3.7 kW) Scott 640cc 2 10 3:31.47 44.86 mph 10 12 Bert Colver 5 hp (3.7 kW) Matchless 666cc 2 10 3:36.46 43.83 mph 11 39 Charlie Murphy 3+2⁄3 hp (2.7 kW) Triumph 499cc 1 10 3:37.15 43.69 mph 12 43 Howard Smith 3+2⁄3 hp (2.7 kW) Triumph 499cc 1 10 3:40.15 43.10 mph 13 27 Jimmy Alexander jun. 5 hp (3.7 kW) Indian 662.5cc 2 10 3:42.49 42.46 mph 14 75 Billy Heaton 3+2⁄3 hp (2.7 kW) NSU 662cc 1 10 3:43.46 42.46 mph 15 62 William McMinnies 3+2⁄3 hp (2.7 kW) Triumph 499cc 1 10 3:45.16 42.14 mph 16 35 Rem Fowler 4 hp (3.0 kW) Rex 660cc 2 10 3:45.46 42.08 mph 17 60 Jack Slaughter 3+2⁄3 hp (2.7 kW) Ariel 482.5cc 1 10 3:48.00 41.46 mph 18 40 Daniel Bolton 4 hp (3.0 kW) Rex 660cc 2 10 3:51.45 40.99 mph 19 40 J.R. Woodward 4 hp (3.0 kW) Rex 660cc 2 10 4:05.51 38.64 mph 20 72 James Baxter 4 hp (3.0 kW) Rex 660cc 2 10 4:07.49 38.33 mph 21 3 G. Lee Evans 5 hp (3.7 kW) Indian 662.5cc 2 10 4:09.16 34.66 mph 22 17 Alfie Alexander 3+2⁄3 hp (2.7 kW) Rex 499cc 1 10 4:10.15 37.93 mph 23 49 W.E. Grange 3+2⁄3 hp (2.7 kW) Rex 499cc 1 10 4:10.37 37.89 mph 24 20 Eric S. Myers 5 hp (3.7 kW) Scott 640cc 2 10 4:16.50 36.99 mph 25 86 Douglas Brown 3+2⁄3 hp (2.7 kW) Humber 499cc 1 10 4:17.30 36.87 mph 26 66 S.C. Perryman 5 hp (3.7 kW) Blumfield 668cc 2 10 4:31.08 34.91 mph 27 19 Andrew Sproston 4 hp (3.0 kW) Rex 660cc 2 10 4:35.06 34.43 mph 28 58 Peter Weatherilt 3+2⁄3 hp (2.7 kW) Zenith-Gradua 482cc 1 10 4:41.53 33.70 mph 29 65 F.W. Case 3+2⁄3 hp (2.7 kW) Centaur 494cc 1 10 4:45.19 33.27 mph Fastest lap: Harold Bowen, 17min. 51sec. 53.15 mph (New record)

• Detailed race results
• Mountain Course map