The enzyme sulfopyruvate decarboxylase (EC 4.1.1.79) catalyzes the chemical reaction

3-sulfopyruvate 2-sulfoacetaldehyde + CO₂

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-sulfopyruvate carboxy-lyase (2-sulfoacetaldehyde-forming). This enzyme is also called sulfopyruvate carboxy-lyase.

• Graupner M, Xu H, White RH (2000). "Identification of the gene encoding sulfopyruvate decarboxylase, an enzyme involved in biosynthesis of coenzyme M". J. Bacteriol. 182 (17): 4862–7. doi:10.1128/JB.182.17.4862-4867.2000. PMC 111365. PMID 10940029.