Route 210 or Highway 210 may refer to:

• BR-210

• Manitoba Provincial Road 210
• Newfoundland and Labrador Route 210
• Nova Scotia Route 210
• Prince Edward Island Route 210
• Quebec Route 210
• Saskatchewan Highway 210

• China National Highway 210

• National Route 210

• Japan National Route 210

• A210 road
• B210 road

• Interstate 210
• U.S. Route 210 (former)
• Alabama State Route 210
• Arizona State Route 210
• California State Route 210
• Florida State Road 210
• Georgia State Route 210 (former)
• Iowa Highway 210
• K-210 (Kansas highway)
• Kentucky Route 210
• Maine State Route 210
• Maryland Route 210
• M-210 (Michigan highway) (former)
• Minnesota State Highway 210
• Missouri Route 210
• Montana Secondary Highway 210
• New Mexico State Road 210
• New York State Route 210
• North Carolina Highway 210
• North Dakota Highway 210
• Oregon Route 210
• Pennsylvania Route 210
• South Carolina Highway 210
• Tennessee State Route 210
• Texas State Highway 210
  • Texas State Highway Loop 210
• Utah State Route 210
• Virginia State Route 210
• West Virginia Route 210
• Wyoming Highway 210