Nettle refers to any of various plant species.

Nettle or nettles may also refer to:

• HMS Nettle, various ships with the name
• USS Nettle, two ships
• USCGC Nettle (WAK-169), a United States Coast Guard coastal freighter

• Nettle Creek (Grass River), a stream in New York, United States
• Nettle Creek (Mad River), a stream in Ohio, United States
• Nettle Creek, Innot Hot Springs, Queensland Australia

• Nettles (surname), a list of people surnamed Nettles or Nettle

• Nettle (cryptographic library), a cryptographic library developed by Niels Möller in 2001
• "Nettles", a song from the single Teddy Picker by the Arctic Monkeys
• Sea nettle, the jellyfish genus Chrysaora

• All pages with titles beginning with Nettle
• All pages with titles containing Nettle
• Nettie (disambiguation)