Cyclic 3-hydroxymelatonin (3-OHM) is a metabolite of melatonin and an antioxidant more potent than melatonin.[1] It is a non-radical species and does not further propagate the radical chain reaction

It is a footprint product of the reaction between melatonin and hydroxyl radical.[2]

References

  1. ^ Tan, Dun-Xian; Hardeland, R.; Manchester, L. C.; Galano, A.; Reiter, R. J. (May 11, 2014). "Cyclic-3-hydroxymelatonin (C3HOM), a potent antioxidant, scavenges free radicals and suppresses oxidative reactions". Current Medicinal Chemistry. 21 (13): 1557–1565. doi:10.2174/0929867321666131129113146. PMID 24304286 – via PubMed.
  2. ^ Tan, Dun-Xian; Manchester, LucienC.; Reiter, RusselJ.; Plummer, BenjaminF. (March 19, 1999). "Cyclic 3-Hydroxymelatonin: A Melatonin Metabolite Generated as a Result of Hydroxyl Radical Scavenging". Biological Signals and Receptors. 8 (1–2): 70–74. doi:10.1159/000014571 (inactive 1 November 2024). PMID 10085465 – via Silverchair.{{cite journal}}: CS1 maint: DOI inactive as of November 2024 (link)
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