The 1942–43 League of Ireland was the 22nd season of senior football in the Republic of Ireland. Cork United were the defending champions.
Changes from 1941–42
No new teams were elected to the League.
Teams
| Team | Location | Stadium |
|---|---|---|
| Bohemians | Dublin (Phibsborough) | Dalymount Park |
| Bray Unknowns | Bray | Carlisle Grounds |
| Brideville | Dublin (The Liberties) | Harold's Cross Stadium |
| Cork United | Cork | Mardyke |
| Drumcondra | Dublin (Clonturk) | Clonturk Park |
| Dundalk | Dundalk | Oriel Park |
| Limerick | Limerick | Markets Field |
| St. James's Gate | Dublin (Drimnagh) | Iveagh Grounds |
| Shamrock Rovers | Dublin (Milltown) | Glenmalure Park |
| Shelbourne | Dublin (Ringsend) | Shelbourne Park |
Season overview
Cork United won their third title, becoming the first team to win three consecutive titles.
Standings
| Pos | Team | Pld | W | D | L | GF | GA | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Cork United | 18 | 12 | 3 | 3 | 42 | 14 | +28 | 27 |
| 2 | Dundalk | 18 | 11 | 4 | 3 | 40 | 22 | +18 | 26 |
| 3 | Drumcondra | 18 | 9 | 5 | 4 | 47 | 34 | +13 | 23 |
| 4 | Shamrock Rovers | 18 | 8 | 4 | 6 | 36 | 28 | +8 | 20 |
| 5 | Shelbourne | 18 | 7 | 5 | 6 | 35 | 28 | +7 | 19 |
| 6 | St James's Gate | 18 | 7 | 4 | 7 | 31 | 30 | +1 | 18 |
| 7 | Limerick | 18 | 8 | 1 | 9 | 41 | 38 | +3 | 17 |
| 8 | Bohemians | 18 | 6 | 4 | 8 | 28 | 34 | −6 | 16 |
| 9 | Brideville | 18 | 3 | 5 | 10 | 25 | 39 | −14 | 11 |
| 10 | Bray Unknowns | 18 | 1 | 1 | 16 | 14 | 72 | −58 | 3 |
Results
Top goalscorers
| Pos | Player | Club | Goals |
|---|---|---|---|
| 1 |   Seán McCarthy
|
Cork United | 16 |