Suppressor of cytokine signaling 4 is a protein that in humans is encoded by the SOCS4 gene.[5]

Function

The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000180008 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000048379 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Suppressor of cytokine signaling 4". Retrieved 2016-02-23.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Suppressor of cytokine signaling 4 (SOCS4)


Allikas: https://en.wikipedia.org/wiki/SOCS4
No tags for this post.