Phospholipase B, also known as lysophospholipase, is an enzyme with a combination of both PLA₁ and PLA₂ activities; that is, it can cleave acyl chains from both the sn-1 and sn-2 positions of a phospholipid. In general, it acts on lysolecithin (which is formed by the action of PLA₂ on lecithin).

• Phospholipase

• Vance JE, Vance DE (14 March 2008). Biochemistry of Lipids, Lipoproteins and Membranes. Elsevier. pp. 312–313. ISBN 978-0-08-055988-9.