Otranto is an unincorporated community and census-designated place in Otranto Township, Mitchell County, in the U.S. state of Iowa. As of the 2020 census the population was 27,^[2] unchanged from 2010.

The community is in northwestern Mitchell County, 7 miles (11 km) northwest of St. Ansgar, the post office serving Otranto, and 18 miles (29 km) northwest of Osage, the county seat. The Minnesota border is 3 miles (5 km) to the north.

Otranto is located along the Cedar River, approximately 4 miles (6 km) southwest of Mona.

As of the census of 2020,^[4] there were 27 people, 14 households, and 13 families residing in the community. The population density was 65.9 inhabitants per square mile (25.4/km²). There were 14 housing units at an average density of 34.1 per square mile (13.2/km²). The racial makeup of the community was 81.5% White, 0.0% Black or African American, 3.7% Native American, 0.0% Asian, 0.0% Pacific Islander, 7.4% from other races and 7.4% from two or more races. Hispanic or Latino persons of any race comprised 11.1% of the population.

Of the 14 households, 21.4% of which had children under the age of 18 living with them, 92.9% were married couples living together, 0.0% were cohabitating couples, 0.0% had a female householder with no spouse or partner present and 7.1% had a male householder with no spouse or partner present. 7.1% of all households were non-families. 7.1% of all households were made up of individuals, 7.1% had someone living alone who was 65 years old or older.

The median age in the community was 54.8 years. 22.2% of the residents were under the age of 20; 0.0% were between the ages of 20 and 24; 7.4% were from 25 and 44; 48.1% were from 45 and 64; and 22.2% were 65 years of age or older. The gender makeup of the community was 51.9% male and 48.1% female.