John Owen may refer to:

• John Owen (footballer) (1849–1921), English footballer and educator
• John Owen (athlete) (1861–1924), American sprinter
• Johnny Owen (1956–1980), Welsh boxer
• John Owen (cricketer) (born 1971), English cricketer

• John Owen (bishop of St Asaph) (1580–1651), Bishop of St Asaph, Wales
• John Owen (theologian) (1616–1683), English Nonconformist church leader and theologian
• John Owen (dean of Clonmacnoise) (1686–1760), Irish Anglican priest
• John Owen (chancellor of Bangor) (1698–1755), Welsh priest and opponent of Methodism
• John Owen (archdeacon of Richmond) (1754–1824), Archdeacon of Richmond and Chaplain General of the British Armed Forces
• John Owen (1766–1822), English Anglican cleric and secretary of the British and Foreign Bible Society
• John Owen (chess player) (1827–1901), English vicar and amateur chess player
• John Owen (bishop of St David's) (1854–1926), Bishop of St David's, Principal of St David's College, Lampeter

• John Owen (theologian) (1616–1683), English religious leader and MP for Oxford University
• John Owen (MP for Caernarvon Boroughs), see Caernarvon Boroughs
• John Lewis Owen, MP for Merioneth
• John Owen (MP for Anglesey and Beaumaris) (died 1754), Welsh politician, represented Anglesey and Beaumaris in Parliament
• Sir John Owen, 1st Baronet (1776–1861), Member of Parliament for Pembroke, 1841–1861
• John Owen (North Carolina politician) (1787–1841), Democratic governor of North Carolina from 1828 to 1830
• John J. Owen (1859–1933), member of the Virginia Senate

• John Dyfnallt Owen (1873–1956), poet and Archdruid
• John Glendwr Owen (1914–1977), British civil servant
• John H. Owen (1922–2011), president of the University of North Georgia and U.S. Navy officer
• John Joseph Thomas Owen (1934 — 2023), British immunologist
• John Owen (author) (1952–2001), dramatist and director
• John Owen (epigrammatist) (c. 1564–1622), Welsh epigrammatist
• John Owen (judge), British barrister, High Court judge, and ecclesiastical judge
• John Owen (Owain Alaw) (1821–1883), Welsh musician and composer
• John Owen (Royal Marines officer) (1777–1857)
• Sir John Owen (1600–1666), Welsh Royalist officer during the English Civil War
• John Simpson Owen (1912–95), Ugandan-born British conservationist
• John Owen (Formula One), British Formula One engineer
• SS John Owen, a Liberty ship

• Johnny Owen (Nebraska politician) (1907–1978), member of the Nebraska House of Representatives
• John Owen-Jones (born 1971), Welsh theatre actor
• Jon Owen, American luger
• Jon Owen Jones (born 1954), Welsh politician
• Jonny Owen (born 1971), Welsh actor
• Jack Owen (disambiguation)
• John Owens (disambiguation)