Martina Trevisan defeated Claire Liu in the final, 6–2, 6–1 to win the singles tennis title at the 2022 Morocco Open. It was her maiden WTA Tour title.^[1]

Maria Sakkari was the defending champion when the tournament was last held in 2019, but she chose not to participate.

	Semifinals							Final
		Martina Trevisan	6	6
		Lucia Bronzetti	3	3
									Martina Trevisan	6	6
									Claire Liu	2	1
		Claire Liu	w/o
	5	Anna Bondár

	First round							Second round							Quarterfinals							Semifinals
	1/WC	G Muguruza	6	6
	LL	A Danilina	3	2				1/WC	G Muguruza	6	4	1
	Q	X You	0	4					M Trevisan	2	6	6
		M Trevisan	6	6												M Trevisan	77	6
		U Eikeri	2	5											7	A Rus	64	3
		D Gálfi	6	7					D Gálfi	4	2
	WC	L Sun	3	0				7	A Rus	6	6
	7	A Rus	6	6																			M Trevisan	6	6
	3	N Párrizas Díaz	77	1	6																		L Bronzetti	3	3
	Q	C Zhao	64	6	2			3	N Párrizas Díaz	4	6	6
		K Mladenovic	6	3	79				K Mladenovic	6	3	0
	LL	T Andrianjafitrimo	3	6	67										3	N Párrizas Díaz	1	6	65
		P Udvardy	64	63												L Bronzetti	6	3	77
		C Burel	77	77					C Burel	3	2
		L Bronzetti	6	65	6				L Bronzetti	6	6
	8	A Kalinskaya	3	77	3

	First round							Second round							Quarterfinals							Semifinals
	9	R Peterson	0	6	5
	WC	P Marčinko	6	2	7			WC	P Marčinko	7	3	3
		M Zacarías	6	5	4				A Sharma	5	6	6
		A Sharma	1	7	6											A Sharma	4	1
		K Rakhimova	4	3												C Liu	6	6
		C Liu	6	6					C Liu	4	77	6
		C Paquet	0	2				4	M Sherif	6	65	1
	4	M Sherif	6	6																			C Liu	w/o
	5	A Bondár	6	3	7																	5	A Bondár
	Q	C Ferrando	4	6	5			5	A Bondár	6	6
		K Kučová	6	6					K Kučová	3	3
		C Harrison	2	0											5	A Bondár	5
		AK Schmiedlová	6	6											2	A Tomljanović	1r
	Q	E Reyngold	1	2					AK Schmiedlová	5	2
		I Burillo Escorihuela	2	1				2	A Tomljanović	7	6
	2	A Tomljanović	6	6

	First round							Qualifying competition
	1	Tessah Andrianjafitrimo	4	7	6
		Ekaterina Yashina	6	5	1
								1	Tessah Andrianjafitrimo	5	6	3
								6	Carol Zhao	7	4	6
	WC	Yasmine Kabbaj	6	5	3
	6	Carol Zhao	3	7	6

	First round							Qualifying competition
	Alt	Ena Shibahara	2	3
		Anna Danilina	6	6
									Anna Danilina	5	1
									Ekaterina Reyngold	7	6
		Ekaterina Reyngold	6	6
	7	Sada Nahimana	3	4

	First round							Qualifying competition
	3	Cristiana Ferrando	6	6
		Paula Kania-Choduń	1	0
								3	Cristiana Ferrando	6	6
									Tara Moore	3	2
		Tara Moore	1	6	6
	8	Ekaterina Kazionova	6	4	0

	First round							Qualifying competition
	4	Yvonne Cavallé Reimers	6	7
		Amina Anshba	3	5
								4	Yvonne Cavallé Reimers	2	4
								5	You Xiaodi	6	6
	WC	Ingrid Neel	64	5
	5	You Xiaodi	77	7

• Main draw
• Qualifying draw