The 2012 Status Athens Open was a professional tennis tournament played on hard courts. It was the fifth edition of the tournament which was part of the 2012 ATP Challenger Tour. It took place in Athens, Greece between 7 and 13 May 2012.
Singles main-draw entrants
Seeds
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 RUS
|
Igor Kunitsyn | 88 | 1 |
 SVK
|
Karol Beck | 111 | 2 |
 EST
|
Jürgen Zopp | 120 | 3 |
 AUS
|
Marinko Matosevic | 122 | 4 |
 BEL
|
Ruben Bemelmans | 145 | 5 |
| RUS
|
Alexander Kudryavtsev | 164 | 6 |
| RUS
|
Konstantin Kravchuk | 190 | 7 |
 LTU
|
Laurynas Grigelis | 193 | 8 |
- 1 Rankings are as of April 30, 2012.
Other entrants
The following players received wildcards into the singles main draw:
Theodoros Angelinos- Konstantinos Economidis
- Alexandros Jakupovic
- Markos Kalovelonis
The following players received entry from the qualifying draw:
Ilija Bozoljac
Aliaksandr Bury
Riccardo Ghedin
Nikolaus Moser
Champions
Singles
- Marinko Matosevic def. Ruben Bemelmans, 6–3, 6–4
Doubles
Andre Begemann / Jordan Kerr def. 
Gerard Granollers / Alexandros Jakupovic, 6–2, 6–3