Arnaud Clément defeated Mario Ančić 7–5, 6–4 to win the 2006 Open 13 singles competition. Joachim Johansson was the champion but did not defend his title.

	Semifinals							Final
	1	Rafael Nadal	6	3	5
	WC	Arnaud Clément	2	6	7
								WC	Arnaud Clément	6	6
								6	Mario Ančić	4	2
	8	Sébastien Grosjean	3	6	3
	6	Mario Ančić	6	3	6

	First round							Second round							Quarterfinals							Semifinals
	1	R Nadal	4	6	7
		O Rochus	6	2	5			1	R Nadal	7	6
	WC	G Simon	4	6	6			WC	G Simon	5	4
		J Nieminen	6	3	2										1	R Nadal	7	6
		P-H Mathieu	5	6	6											P-H Mathieu	5	4
	Q	J Haehnel	7	3	4				P-H Mathieu	77	6
		T Berdych	5	4				7	R Štěpánek	60	3
	7	R Štěpánek	7	6																		1	R Nadal	6	3	5
	4	T Johansson	4	63																		WC	A Clément	2	6	7
		F Santoro	6	77					F Santoro	6	6
	Q	N Thomann	3	2					G Rusedski	3	2
		G Rusedski	6	6												F Santoro	5	6	65
		J Melzer	4	63											WC	A Clément	7	4	77
		F Verdasco	6	77					F Verdasco	65	3
	WC	A Clément	3	6	6			WC	A Clément	77	6
	5	R Gasquet	6	4	0

	First round							Second round							Quarterfinals							Semifinals
	8	S Grosjean	2	7	6
		G Monfils	6	5	3			8	S Grosjean	6	6
	Q	S de Chaunac	4	3					M Youzhny	3	1
		M Youzhny	6	6											8	S Grosjean	77	6
	LL	E Korolev	2	6	6										LL	E Korolev	64	3
	Q	A Sidorenko	6	4	1			LL	E Korolev	6	78
		C Rochus	1	2				3	N Davydenko	4	66
	3	N Davydenko	6	6																		8	S Grosjean	3	6	3
	6	M Ančić	6	69	6																	6	M Ančić	6	3	6
		M Baghdatis	2	711	4			6	M Ančić	6	6
	Q	J-C Faurel	6	6				Q	J-C Faurel	3	3
		F López	3	3											6	M Ančić	77	3	6
		T Dent	6	3	60										2	I Ljubičić	62	6	3
		I Andreev	2	6	77				I Andreev	65	4
		P Srichaphan	3	78	3			2	I Ljubičić	77	6
	2	I Ljubičić	6	66	6

• Association of Tennis Professionals (ATP) draw
• Association of Tennis Professionals (ATP) Qualifying draw