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The third paragraph under "Functions" starts with, 'It also contains a substance which if injected intravenously causes fall of blood-pressure.' Is this supposed to refer to the correlation between blood pressure and Melatonin production?

The description in "Functions" is vague. Melatonin usally increases potassium channel conductance thereby slowing down the heart rate and possibly relaxing the endothelium (haven't checked this). moosattack

There is no reputable evidence that fluoride has any influence on humman sexual maturity. In fact, the contrary exists. So, let's just drop this line in the article until peer-reviewed data is available.

The third sentence in the lede states "The shape and size of the gland make it resemble a pine nut, inferring its name." However, under the heading "Structure", the second sentence states "It takes its name from its pine-cone shape." Both assertions are properly sourced, but those sources differ. Of course, a pine nut and a pine-cone are both prolate spheroids, but pine-cones exhibit far more variety in their shapes than do pine nuts. Anyone have any thoughts about how to resolve this contradiction? Bricology (talk) 08:20, 27 October 2018 (UTC)[reply]

Bricology -- thanks for pointing this out. The one book referring to the gland shape as a pine nut must have been in error (pine nut shape here is nothing like the shape of the pineal gland), and I have replaced it with an etymology source and subsection. All references I consulted refer to the shape as a pine cone, and the anatomy of the pineal clearly shows its shape as a cone. --Zefr (talk) 17:04, 27 October 2018 (UTC)[reply]

"Calcium and phosphorus deposits in the pineal gland have been correlated with aging" - based on an inactive source from 2006, meanwhile this paper from 2017 says that "There was no statistically significant correlation between age and the extent of the calcification.". How do we resolve it? SkywalkerPL (talk) 11:27, 27 December 2018 (UTC)[reply]

The source that is given that states that calcification is typical says "The majority of patients included in the study had a history of seizures or minor head injury." There should be a study cited that studied people with no history of issues relating to the brain. The source I cite here says that "The human pineal body begins to undergo extensive calcification during the second decade of life" but I can't access the source it cites because you need to pay. RICHARD J. WURTMAN, M.D., JULIUS AXELROD, Ph.D., JACK D. BARCHAS, M.D., Age and Enzyme Activity in the Human Pineal, The Journal of Clinical Endocrinology & Metabolism, Volume 24, Issue 3, 1 March 1964, Pages 299–301, https://doi.org/10.1210/jcem-24-3-299 I found that source from: https://www.researchgate.net/publication/18732983_Incidence_of_normal_pineal_gland_calcification_in_skull_roentgenograms_of_Black_and_White_Americans Possibly can add more info using it.

In footnote [7], the referenced article doesn't seem to discuss "A few more developed vertebrates have lost pineal glands over the course of their evolution" like the statement states. Correction needed here I think! See, "A few more developed vertebrates have lost pineal glands over the course of their evolution.[7]".

If I am wrong or you find the correct article indicated what the statement says, I would love to hear about it. — Preceding unsigned comment added by 73.153.146.226 (talk) 02:29, 26 July 2020 (UTC)[reply]

Why is Descartes mind/body diagram on this page? I don't see how it has anything to do with the Pineal gland.