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The third paragraph under "Functions" starts with, 'It also contains a substance which if injected intravenously causes fall of blood-pressure.' Is this supposed to refer to the correlation between blood pressure and Melatonin production?

The description in "Functions" is vague. Melatonin usally increases potassium channel conductance thereby slowing down the heart rate and possibly relaxing the endothelium (haven't checked this). moosattack

There is no reputable evidence that fluoride has any influence on humman sexual maturity. In fact, the contrary exists. So, let's just drop this line in the article until peer-reviewed data is available.

The third paragraph of the lede addresses two issues: that the pineal body is an atrophied vestige of something, and then the part about Decartes. Since these two things have nothing in common with each other, they should at least be separate paragraphs. Furthermore, the first part looks about 50-100 years out of date. "the pineal gland represents a kind of atrophied photoreceptor" "linked to a vestigial organ, known as the parietal eye." In many vertebrates the parietal eye is fully functional. It is generally a non-image-forming light-detecting organ used to regulate circadian rhythm. It evolved long after the eye. Apparently warm-blooded animals don't need one. At one time scientists threw around words like "atrophied" and "vestigial" whenever they encountered something they didn't understand. In other words, it was the default assumption. Nowadays using such terminology is considered an extraordinary claim requiring extraordinary evidence. Zyxwv99 (talk) 02:16, 13 November 2015 (UTC)[reply]

In pop culture? Yeah, sounds odd, but the Pineal Gland does play a decent role in the "religion" Discordianism. Here is but one reference - Google provides forth with more: http://discordia.wikia.com/wiki/Pineal_gland I'll leave it to others to discuss notability. However, this may be the closest this topic comes to non-academic fame. Reverend Loki (talk) 22:04, 29 March 2016 (UTC)[reply]