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I think this article is in desperate need of images. The description of where this important gland sounds like ancient Greek to someone that knows nothing about the brain and it's anatomy. JoeHenzi 18:40, 5 Apr 2005 (UTC)

The third paragraph under "Functions" starts with, 'It also contains a substance which if injected intravenously causes fall of blood-pressure.' Is this supposed to refer to the correlation between blood pressure and Melatonin production?

The description in "Functions" is vague. Melatonin usally increases potassium channel conductance thereby slowing down the heart rate and possibly relaxing the endothelium (haven't checked this). moosattack

There is no reputable evidence that fluoride has any influence on humman sexual maturity. In fact, the contrary exists. So, let's just drop this line in the article until peer-reviewed data is available.

I have removed the following section from the article. This is primary research (WP:MEDRS). --LT910001 (talk) 03:06, 23 February 2014 (UTC)[reply]

Role in dimethyltryptamine production

Dr. Rick Strassman, who conducted research on the psychedelic dimethyltryptamine (DMT) in the 1990s at the University of New Mexico, has speculated that the pineal gland plays a role in the production of DMT in the human brain. Strassman has also advanced the controversial hypothesis that a massive release of DMT from the pineal gland prior to death, or near death, can result in a near-death experience (NDE). Strassman has suggested that the pineal gland is responsible for DMT production because enzymatic material needed to produce DMT is found there (see evidence in mammals) in substantially greater concentrations than in any other part of the body, Strassman (p. 69^[1]). In 2013, researchers first reported DMT in the pineal gland microdialysate of rodents.^[2]

I have replaced the said removed section.WP:MEDRS recommends the removal of primary sources where they conflict with the conclusions found in secondary research articles:

If the conclusions of the research are worth mentioning, they should be described as being from a single study, for example:

"A 2009 U.S. study found the average age of formal autism spectrum diagnosis was 5.7 years." (citing PMID 19318992) After enough time has passed for a review in the area to be published, the review should be cited in preference to the primary study. Using a secondary source often allows the fact to be stated with greater reliability:

"In the U.S., the average age of formal autism spectrum diagnosis is 5.7 years." (citing a review)

Furthermore WP:MEDRS states:

"Assessing evidence quality" means that editors should determine the quality of the type of study. Editors should not perform a detailed academic peer review. Do not reject a high-quality type of study due to personal objections to the study's inclusion criteria, references, funding sources, or conclusions.

Please refer to the archived Pineal Gland and DMT discussions before deeming the entire section not worth mentioning. Spincredulous (talk) 04:32, 5 March 2014 (UTC)[reply]