Olivetolic acid is an organic compound with the formula C5H11C6H2(OH)2CO2H. Several isomers with this formula exist. Olivetolic acid can be viewed as a derivative of olivetol ( 1,3,5-C5H11C6H2(OH)2CO2H, with a carboxylic acid group adjacent to the pentyl (C5H11) group. Olivetolic acid has attracted attention because it is an intermediate in the biosynthetic pathway of the cannabinoids, found in Cannabis sativa.[1]

The ester dimer of olivetolic acid, anziaic acid, is found in lichen.[2][3]

References

  1. ^ Fellermeier, Monika; Zenk, Meinhart H (May 1998). "Prenylation of olivetolate by a hemp transferase yields cannabigerolic acid, the precursor of tetrahydrocannabinol". FEBS Letters. 427 (2): 283–285. doi:10.1016/S0014-5793(98)00450-5. PMID 9607329.
  2. ^ Cheng, Bokun; Cao, Shugeng; Vasquez, Victor; Annamalai, Thirunavukkarasu; Tamayo-Castillo, Giselle; Clardy, Jon; Tse-Dinh, Yuk-Ching (8 April 2013). "Identification of Anziaic Acid, a Lichen Depside from Hypotrachyna sp., as a New Topoisomerase Poison Inhibitor". PLOS ONE. 8 (4): e60770. Bibcode:2013PLoSO...860770C. doi:10.1371/journal.pone.0060770. PMC 3620467. PMID 23593306.
  3. ^ M.P. Polovinka; N.I. Komarova; D.V. Korchagina; D.N. Sokolov; O.A. Luzina; N.G. Vlasenko; A.A. Malyuga; E.V. Romanova; N.F. Salakhutdinov: Secondary metabolites of the lichen Cladonia stellaris in Chemistry of Natural Compounds 48 (2012) 392–395, doi:10.1007/s10600-012-0259-4.
Allikas: https://en.wikipedia.org/wiki/Olivetolic_acid
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