Nitromersol (metaphen) is a mercury-containing organic compound that is primarily used as an antiseptic and disinfectant. It is a brown-yellow solid that has no odor or taste, does not irritate the skin or mucous membranes, and has no impact on rubber or metallic instruments, including surgical and dental tools.[1]

This compound is a confirmed animal carcinogen. It can emit toxic fumes of NOx and mercury vapor when heated.[2] In 1998, use of nitromersol (and other mercury-containing products) as OTC first-aid antiseptics and products for diaper rash and vaginal contraceptives was disallowed by the FDA.[3] Nitromersol can cause hypersensitivity reactions.[4]

It is still in use as a preservative for vaccines and antitoxins.[examples needed][citation needed]

See also

  • Thiomersal – Organomercury antiseptic and antifungal agent
  • Phenylmercuric nitrate - an organomercury compound with powerful antiseptic and antifungal effects

References

  1. ^ Hospital formulary and compendium of useful information. Berkeley, California: University of California Press. 1941. p. 113. Retrieved 2011-04-08.
  2. ^ Lewis, Richard J. (2008). Hazardous chemicals desk reference. Wiley-Interscience. p. 1018. ISBN 978-0-470-18024-2. Retrieved 2011-04-08.
  3. ^ Remington: the science and practice of pharmacy. Medicine Series. Vol. 1 (21st ed.). Lippincott Williams & Wilkins. 2005. p. 369. ISBN 0-7817-4673-6.
  4. ^ Trevor, Anthony J.; Katzung, Bertram G.; Masters, Susan B. (2007). Katzung & Trevor's pharmacology: examination & board review. Lange Basic Science (8th ed.). McGraw-Hill Professional. p. 420. ISBN 978-0-07-148869-3.
Allikas: https://en.wikipedia.org/wiki/Nitromersol
No tags for this post.