Matlock may refer to:

• Matlock (1986 TV series), American television series
  • Ben Matlock, the title character of the TV series by the same name
• Matlock (2024 TV series), a reboot of the original series

• Matlock, Derbyshire, a town in England
  • Matlock Bath, a village south of Matlock, Derbyshire, England
  • Matlock Bank, an area on a hill in Matlock, Derbyshire, England
  • Matlock Bridge, a bridge and surrounding area in Matlock, Derbyshire, England
• Matlock, Iowa, a small city in the United States
• Matlock, Manitoba, a community in Canada
• Matlock, Victoria, a town in Australia
• Matlock, Washington, a small town in the United States

• Matlock (surname)

• Matlock Cable Tramway, cable tramway that served the town of Matlock between 1893 and 1927
• Matlock Town F.C., a football club in Matlock, England
• United States v. Matlock (1974), a Supreme Court case
• "Matlock", the tripcode of the persona behind QAnon