The following highways are numbered 61:

• AH61 Asian Highway 61
• E61 European route E61

• Alberta Highway 61
• Newfoundland and Labrador Route 61
• Ontario Highway 61

• Bauta–Baracoa Road (2–61)

• National Highway 61 (India)
• State Highway 61 (Kerala)
• State Highway 61 (Rajasthan)

• National Route 61

• State Highway 61 (New Zealand)

• N61 highway (Philippines)

• Expressway S61
• National road 61

• British A61
• British M61

• U.S. Route 61
• Alabama State Route 61
• Arizona State Route 61
• California State Route 61
• Colorado State Highway 61
• Connecticut Route 61
• Florida State Road 61
  • Florida State Road 61A
  • County Road 61 (Wakulla County, Florida)
• Georgia State Route 61
• Hawaii Route 61
• Idaho State Highway 61
• Illinois Route 61
• Indiana State Road 61
• K-61 (Kansas highway)
• Kentucky Route 61
• Louisiana State Route 61 (former)
• Maryland Route 61
• M-61 (Michigan highway)
• Minnesota State Highway 61
  • County Road 61 (Hennepin County, Minnesota)
  • County Road 61 (Lake County, Minnesota)
  • County Road 61 (Pine County, Minnesota)
  • County Road 61 (St. Louis County, Minnesota)
• Missouri Route 61 (1922) (former)
• Nebraska Highway 61
  • Nebraska Link 61D
  • Nebraska Spur 61A
• Nevada State Route 61 (former)
• County Route 61 (Bergen County, New Jersey)
• New Mexico State Road 61
• New York State Route 61
  • County Route 61 (Chautauqua County, New York)
  • County Route 61 (Columbia County, New York)
  • County Route 61 (Dutchess County, New York)
  • County Route 61 (Greene County, New York)
  • County Route 61 (Madison County, New York)
  • County Route 61 (Onondaga County, New York)
  • County Route 61 (Orange County, New York)
  • County Route 61 (Putnam County, New York)
  • County Route 61 (Schoharie County, New York)
  • County Route 61 (Suffolk County, New York)
  • County Route 61 (Sullivan County, New York)
  • County Route 61 (Washington County, New York)
• North Carolina Highway 61
• North Dakota Highway 61 (former)
• Ohio State Route 61
• Oklahoma:
  • Oklahoma State Highway 61 (1934–1941) (former)
  • Oklahoma State Highway 61 (1944–1968) (former)
  • Oklahoma State Highway 61A (former)
• Pennsylvania Route 61
• South Carolina Highway 61
• South Dakota Highway 61 (former)
• Tennessee State Route 61
• Texas State Highway 61
  • Texas State Highway Loop 61 (former)
  • Farm to Market Road 61
  • Texas Park Road 61
• Utah State Route 61
• Virginia State Route 61
• West Virginia Route 61
• Wisconsin Highway 61 (former)

• A61
• Highway 61 (disambiguation)
• Route 61 (disambiguation)