The following highways are numbered 285:

• BR-285

• Manitoba Provincial Road 285
• Quebec Route 285

• R285 regional road

• Japan National Route 285

• Interstate 285 (multiple highways)
• U.S. Route 285
• Alabama State Route 285
• California State Route 285 (former)
• Florida State Road 285
• Georgia State Route 285
• Iowa Highway 285 (former)
• K-285 (Kansas highway)
• Kentucky Route 285
• Maryland Route 285
• Montana Secondary Highway 285
• New York State Route 285 (former)
• Ohio State Route 285
• Pennsylvania Route 285
• Tennessee State Route 285
• Texas State Highway 285
  • Texas State Highway Loop 285
  • Farm to Market Road 285 (Texas)
• Utah State Route 285
• Virginia State Route 285
• Washington State Route 285