Isoserine is a non-proteinogenic α-hydroxy-β-amino acid, and an isomer of serine. Non-proteinogenic amino are not part of the genetic code of any known organism and are only present in proteins if added post-translationally. Isoserine has only been produced synthetically.

The first documented synthesis of isoserine in a laboratory setting was by Miyazawa et al., who published their results in 1976.[1]

See also

References

  1. ^ Ziora, Zyta; Skwarcynski, Mariusz; Kiso, Yoshiaki (2011). "Medicinal Chemistry of α-Hydroxy-β-Amino Acids". In Hughes, Andrew B. (ed.). Amino Acids, Peptides and Proteins in Organic Chemistry, Volume 4: Protection, Reactions, Medicinal Chemistry, Combinatorial Synthesis. Wiley-VCH. Section 6.2.2: Synthesis of α-Hydroxy-β-amino acids. ISBN 978-3-527-63182-7. OCLC 741558720. Retrieved 2017-06-10 – via Google Books.


Allikas: https://en.wikipedia.org/wiki/Isoserine
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