Number 1s, #1s or Number Ones may refer to:
- A type of greatest hits album in which all or most of the songs were number-one chart hits. Among them are:
- Number Ones (ABBA album), 2006
- Number Ones (Bee Gees album), 2004
- #1's (Destiny's Child album), 2005
- Number Ones (Janet Jackson album), 2009
- #1's (Mariah Carey album), 1998
- Number Ones (Michael Jackson album), 2003
- Number Ones (video), the related DVD by Michael Jackson
- Reba #1's, an album by Reba McEntire
- Number 1's (Prince Royce album)
- #1s... and Then Some, an album by Brooks & Dunn
- Number Ones (TV series), a Canadian music-video program
- The Number Ones, an album by the Beatles