François (French: [fʁɑ̃swa]) is a French masculine given name and surname, equivalent to the English name Francis.

• François Amoudruz (1926–2020), French resistance fighter
• François-Marie Arouet (better known as Voltaire; 1694–1778), French Enlightenment writer, historian, and philosopher
• François Beauchemin (born 1980), Canadian ice hockey player for the Anaheim Ducks
• François Blanc (1806–1877), French entrepreneur and operator of casinos
• François Bonlieu (1937–1973), French alpine skier
• François Cevert (1944–1973), French racing driver
• François Chau (born 1959), Cambodian American actor
• François Clemmons (born 1945), American singer and actor
• François Corbier (1944–2018), French television presenter and songwriter
• François Coty (1874–1934), French perfumer
• François Coulomb the Elder (1654–1717), French naval architect
• François Coulomb the Younger (1691–1751), French naval architect
• François Couperin (1668–1733), French Baroque composer, keyboardist
• François Couturier (born 1950), French jazz pianist
• François Henricus Anthonie van Dixhoorn (born 1948), Dutch poet
• François de Klerk (born 1991), South African rugby player
• François "Faf" du Plessis (born 1984), South African cricketer
• François Englert (born 1932), Belgian particle physicist who in 2013 shared the Nobel Prize with Peter Higgs
• François Feldman (born 1958), French singer
• François Gautier (born 1950), French journalist
• François Gernigon (born 1961), French politician
• François Lalande (1930–2020), French actor
• François Lapointe (politician) (born 1971), Canadian politician
• François Lapointe (racewalker) (born 1961), Canadian racewalker
• François Laroque (born 1948), French academic, translator and Shakespeare specialist
• François Lavoie (born 1993), Canadian ten-pin bowler
• François Leterrier (1929–2020), French film director and actor
• François Lionet (born 1963), French computer programmer
• François Locufier, French cartoonist
• François Pienaar (born 1965), South African rugby player
• François Pinault (born 1936), French billionaire
• François-Henri Pinault (born 1962), French billionaire
• François Prelati, Italian cleric and alchemist
• François Quesnay (1694–1774), French economist
• François Rabbath (born 1931), French double-bass player and composer
• François Rabelais (died 1553), French Renaissance writer, doctor and humanist
• François-Xavier Roth (born 1971), French conductor
• François Rozenthal (born 1975), French ice hockey player
• François Ruffin (born 1975), French journalist, filmmaker, author and politician
• François Sagat (born 1979), French model and porn actor
• François Steyn (born 1987), South African rugby player
• François Vincent Henri Antoine de Stuers (1792-1881), Dutch general
• François Tracanelli (born 1951), French pole vaulter
• François Trinh-Duc (born 1986), French rugby player
• François Truffaut (1932-1984), French film director, screenwriter, producer, actor and film critic
• François Vérove (1962–2021), French serial killer
• François Vidal (1832–1911), French poet
• François van 't Sant (1883–1966), Dutch spy and police commissioner

• Francis I of France (1494–1547), King of France (r. 1515–1547), known as "the Father and Restorer of Letters"
• Francis II of France (1554–1560), King of France and King consort of Scots (r. 1558–1560), known as the husband of Mary Stuart, Queen of Scots
• François Fillon (born 1954), Prime Minister of France 2007–2012
• François Hollande (born 1954), President of France 2012–2017
• François Mitterrand (1916–1996), President of France 1981–1995

• François Denys Légitime (1841–1935), President of Haiti from 1888 to 1889
• François Duvalier (1907–1971), President of Haiti from 1957 to 1971

• Francois Turbot, a recurring character in the Canadian television series PAW Patrol

• François Aubry (disambiguation), several people
• François Baby (disambiguation), several people
• François Boucher (disambiguation), several people
• François Caron (disambiguation), several people
• François Dominique (disambiguation), several people
• François Duval (disambiguation), several people
• François Fournier (disambiguation), several people

• Abraham François (born 1977), Canadian soccer player
• Alexandre François, French linguist
• André François (1915-2005), Hungarian-born French cartoonist
• Christian Francois (born 1985), volleyball player from Trinidad and Tobago
• Claude François (1939-1978), French pop singer
• Déborah François (born 1987), Belgian actress
• Deondre Francois (born 1997), Haitian-born American football player
• Elvis Francois (born 1985), American orthopedic surgeon and singer
• Guillaume François (born 1990), Belgian professional footballer
• Hermann von François (1856–1933), German general during WW1
• Hunter J. Francois (1924-2014), Saint Lucian politician
• Jacques François (1920-2003), French actor
• Jacques Francois (footballer) (born 1992), Haitian football player
• Julien François (born 1979), French footballer
• Kendall Francois (1971-2014), serial killer from Poughkeepsie, New York
• Mark François (born 1965), British politician
• Tony François (born 1971), Mauritian international footballer

• "Citizen François", a caricatural personification of Revolutionary France by James Gillray
• François, Deux-Sèvres, a municipality in the Poitou-Charentes region, France
• Francois, Newfoundland and Labrador, a settlement in Canada
• Le François, a town on the island of Martinique, France
• Lefrançois, a French surname
• Saint-François (disambiguation)
• Frànçois & the Atlas Mountains
• françois (language) [fr] (IPA [frãˈs(w)ɛ]), a common name describing the French language before the reform of French orthography in 1835.