9-Phenanthrol is an aromatic alcohol derived from phenanthrene, a tricyclic compound. It is a TRPM4 channel inhibitor.[1] It can prevent the pancreas from secreting insulin when stimulated by glucose.[2]

References

  1. ^ Guinamard, R; Hof, T; Del Negro, C A (2014). "The TRPM4 channel inhibitor 9-phenanthrol". British Journal of Pharmacology. 171 (7): 1600–1613. doi:10.1111/bph.12582. PMC 3966741. PMID 24433510.
  2. ^ Ma, Zuheng; Björklund, Anneli; Islam, Md. Shahidul (2017). "A TRPM4 Inhibitor 9-Phenanthrol Inhibits Glucose- and Glucagon-Like Peptide 1-Induced Insulin Secretion from Rat Islets of Langerhans". Journal of Diabetes Research. 2017: 1–5. doi:10.1155/2017/5131785. PMC 5643033. PMID 29098165.
Allikas: https://en.wikipedia.org/wiki/9-phenanthrol
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