3-Hydroxypropionyl-CoA synthase (EC 6.2.1.36, 3-hydroxypropionyl-CoA synthetase (AMP-forming), 3-hydroxypropionate-CoA ligase) is an enzyme with systematic name hydroxypropionate:CoA ligase (AMP-forming).[1][2] This enzyme catalyses the following chemical reaction
- 3-hydroxypropionate + ATP + CoA 3-hydroxypropionyl-CoA + AMP + diphosphate
This enzyme catalyses a step in the 3-hydroxypropionate/4-hydroxybutyrate cycle.
References
- ^ Berg IA, Kockelkorn D, Buckel W, Fuchs G (December 2007). "A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea". Science. 318 (5857): 1782–6. doi:10.1126/science.1149976. PMID 18079405.
- ^ Alber BE, Kung JW, Fuchs G (February 2008). "3-Hydroxypropionyl-coenzyme A synthetase from Metallosphaera sedula, an enzyme involved in autotrophic CO2 fixation". Journal of Bacteriology. 190 (4): 1383–9. doi:10.1128/JB.01593-07. PMC 2238213. PMID 18165310.
External links
- 3-hydroxypropionyl-CoA+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
