Neal Skupski and Desirae Krawczyk defeated Joe Salisbury and Harriet Dart in the final, 6–2, 7–6^(7–1), to win the mixed doubles tennis title at the 2021 Wimbledon Championships. It was Krawczyk's second consecutive major title in mixed doubles, following her success at the French Open.^[1]

Ivan Dodig and Latisha Chan were the defending champions from when the tournament was last held in 2019,^[2] but lost in the third round to John Peers and Zhang Shuai.

All seeds received a bye into the second round.

Click on the seed number of a player to go to their draw section.

	Quarterfinals							Semifinals							Final
	14	Jean-Julien Rojer Andreja Klepač	66	2
	7	Neal Skupski Desirae Krawczyk	78	6
								7	Neal Skupski Desirae Krawczyk	3	77	7
								17	John Peers Zhang Shuai	6	64	5
	4	Édouard Roger-Vasselin Nicole Melichar	2	4
	17	John Peers Zhang Shuai	6	6
															7	Neal Skupski Desirae Krawczyk	6	77
																Joe Salisbury Harriet Dart	2	61
	WC	Jérémy Chardy Naomi Broady	6	4	5
		Joe Salisbury Harriet Dart	4	6	7
									Joe Salisbury Harriet Dart	6	4	6
								9	Kevin Krawietz Květa Peschke	2	6	4
	9	Kevin Krawietz Květa Peschke	6	63	9
	2	Mate Pavić Gabriela Dabrowski	3	77	7

	First round							Second round							Third round							Quarterfinals
								Alt	A McHugh E Webley-Smith	3	1
	PR	R Bopanna S Mirza	6	77				PR	R Bopanna S Mirza	6	6
	Alt	R Ramanathan A Raina	2	65											PR	R Bopanna S Mirza	3	6	9
		J Erlich L Hradecká	77	65	4										14	J-J Rojer A Klepač	6	3	11
	PR	G Escobar V Zvonareva	65	77	6			PR	G Escobar V Zvonareva	65	4
								14	J-J Rojer A Klepač	77	6
																						14	J-J Rojer A Klepač	66	2
																						7	N Skupski D Krawczyk	78	6
								12	F Martin A Guarachi	3	3
		K Skupski J Pegula	1	7	5			Alt	A Fery T Moore	6	6
	Alt	A Fery T Moore	6	5	7										Alt	A Fery T Moore	65	3
	WC	L Glasspool J Burrage													7	N Skupski D Krawczyk	77	6
		L Bambridge A Muhammad	w/o						L Bambridge A Muhammad	3	67
								7	N Skupski D Krawczyk	6	79

	First round							Second round							Third round							Quarterfinals
								4	É Roger-Vasselin N Melichar	w/o
		A Krajicek S Santamaria	3	6	5			WC	N Kyrgios V Williams
	WC	N Kyrgios V Williams	6	3	7										4	É Roger-Vasselin N Melichar	6	4	6
		J-P Smith C McNally	2	3												A Vasilevski Ar Rodionova	2	6	4
		A Vasilevski Ar Rodionova	6	6					A Vasilevski Ar Rodionova	w/o
								Alt	Bye
																						4	É Roger-Vasselin N Melichar	2	4
																						17	J Peers S Zhang	6	6
								17	J Peers S Zhang	6	6
		R Jebavý M Vondroušová	6	3	6				R Jebavý M Vondroušová	2	3
	Alt	A Begemann V Heisen	4	6	3										17	J Peers S Zhang	6	77
		A-u-H Qureshi N Kichenok	w/o												6	I Dodig L Chan	4	64
		A Bublik A Pavlyuchenkova							A-u-H Qureshi N Kichenok	65	4
								6	I Dodig L Chan	77	6

	First round							Second round							Third round							Quarterfinals
									bye
	WC	R Peniston E Silva	4	2				WC	J Chardy N Broady	w/o
	WC	J Chardy N Broady	6	6											WC	J Chardy N Broady	6	7
	Alt	D Sharan S Murray Sharan	6	5	6										10	R Klaasen D Jurak	3	5
	PR	A Behar G Voskoboeva	3	7	4			Alt	D Sharan S Murray Sharan	6	61	3
								10	R Klaasen D Jurak	3	77	6
																						WC	J Chardy N Broady	6	4	5
																							J Salisbury H Dart	4	6	7
									bye
		O Marach L Kichenok	7	7					O Marach L Kichenok	w/o
		S González G Olmos	5	5												O Marach L Kichenok	3	77	3
		J Salisbury H Dart	6	77												J Salisbury H Dart	6	64	6
		H Kontinen H Watson	1	63					J Salisbury H Dart	6	1	6
								3	W Koolhof D Schuurs	2	6	4

	First round							Second round							Third round							Quarterfinals
								5	R Ram B Mattek-Sands	6	3	6
		N Monroe R Voráčová	6	6					N Monroe R Voráčová	3	6	4
	WC	J O'Mara SB Grey	4	3											5	R Ram B Mattek-Sands
	PR	M López M Bouzková	3	4											9	K Krawietz K Peschke	w/o
		M Purcell M Kostyuk	6	6					M Purcell M Kostyuk
								9	K Krawietz K Peschke	w/o
																						9	K Krawietz K Peschke	6	63	9
																						2	M Pavić G Dabrowski	3	77	7
								13	S Gillé H Carter	6	3	6
		M Demoliner L Stefani	6	6					M Demoliner L Stefani	2	6	3
	Alt	D Pel R van der Hoek	3	2											13	S Gillé H Carter	4	4
		M Middelkoop K Bertens	63	7	3										2	M Pavić G Dabrowski	6	6
		M Ebden S Stosur	77	5	6				M Ebden S Stosur	5	68
								2	M Pavić G Dabrowski	7	710

During the tournament

• 2021 Wimbledon Championships – Day-by-day summaries

• Mixed Doubles draw