Novak Djokovic defeated the two-time defending champion Roger Federer in the final, 7–6^(8–6), 7–5 to win the singles tennis title at the 2012 ATP World Tour Finals.^[1][2][3] It was his second Tour Finals title.

Janko Tipsarević made his debut as a direct qualifier, after playing two matches as an alternate in 2011.

	Semifinals							Final
	1	Novak Djokovic	4	6	6
	6	Juan Martín del Potro	6	3	2
								1	Novak Djokovic	78	7
								2	Roger Federer	66	5
	2	Roger Federer	77	6
	3	Andy Murray	65	2

		Djokovic	Murray	Berdych	Tsonga	RR W–L	Set W–L	Game W–L	Standings
1	Novak Djokovic		4–6, 6–3, 7–5	6–2, 7–6(8–6)	7–6(7–4), 6–3	3–0	6–1 (85.7%)	43–31 (58.1%)	1
3	Andy Murray	6–4, 3–6, 5–7		3–6, 6–3, 6–4	6–2, 7–6(7–3)	2–1	5–3 (62.5%)	42–38 (52.5%)	2
5	Tomáš Berdych	2–6, 6–7(6–8)	6–3, 3–6, 4–6		7–5, 3–6, 6–1	1–2	3–5 (37.5%)	37–40 (48.1%)	3
7	Jo-Wilfried Tsonga	6–7(4–7), 3–6	2–6, 6–7(3–7)	5–7, 6–3, 1–6		0–3	1–6 (14.3%)	29–42 (40.8%)	4

Standings are determined by: 1. number of wins; 2. number of matches; 3. in two-players-ties, head-to-head records; 4. in three-players-ties, percentage of sets won, or of games won initially to sort out a superior/inferior player, then head-to-head records; 5. ATP rankings.

		Federer	Ferrer	Del Potro	Tipsarević	RR W–L	Set W–L	Game W–L	Standings
2	Roger Federer		6–4, 7–6(7–5)	6–7(3–7), 6–4, 3–6	6–3, 6–1	2–1	5–2 (71.4%)	40–31 (56.3%)	1
4	David Ferrer	4–6, 6–7(5–7)		6–3, 3–6, 6–4	4–6, 6–3, 6–1	2–1	4–4 (50.0%)	41–36 (53.2%)	3
6	Juan Martín del Potro	7–6(7–3), 4–6, 6–3	3–6, 6–3, 4–6		6–0, 6–4	2–1	5–3 (62.5%)	42–34 (55.3%)	2
8	Janko Tipsarević	3–6, 1–6	6–4, 3–6, 1–6	0–6, 4–6		0–3	1–6 (14.3%)	18–40 (31.0%)	4

Standings are determined by: 1. number of wins; 2. number of matches; 3. in two-players-ties, head-to-head records; 4. in three-players-ties, percentage of sets won, or of games won initially to sort out a superior/inferior player, then head-to-head records; 5. ATP rankings.

• Main draw