Seven Year Itch may refer to:

• The Seven Year Itch (play), by George Axelrod, 1952
• The Seven Year Itch, a 1955 film based on the play
• Seven Years Itch, a film by Johnnie To, 1987
• "The Seven Year Itch" (Grimm), a 2017 TV episode

• Seven Year Itch: 1982–1989, a 1999 compilation album by Platinum Blonde
• Seven Year Itch: Greatest Hits, 1994–2001, a 2001 compilation album by Collective Soul
• The Seven Year Itch (Angelica album), 2002
• The Seven Year Itch (Siouxsie and the Banshees album), 2003
• Seven Year Itch (Etta James album), 1988

• Seven-year itch (idiom), a term that suggests that happiness declines after around year seven of a marriage
• Scabies, or seven-year itch, a parasitic skin infection

• All pages with titles containing seven year itch
• 7 Year Bitch, an American music group