Rafael Nadal defeated David Nalbandian in the final, 6–2, 6–3 to win the singles tennis title at the 2013 Brasil Open.

Nicolás Almagro was the two-time defending champion, but lost in the quarterfinals to Nalbandian.

	Semifinals							Final
	1/WC	Rafael Nadal	6	62	6
	LL	Martín Alund	3	77	1
								1/WC	Rafael Nadal	6	6
									David Nalbandian	2	3
		Simone Bolelli	3	5
		David Nalbandian	6	7

	First round							Second round							Quarterfinals							Semifinals
								1/WC	R Nadal	6	6
		R Ramírez Hidalgo	66	0r				Q	J Souza	3	4
	Q	J Souza	78	0											1/WC	R Nadal	3	6	6
		A Kuznetsov	3	4												C Berlocq	6	4	4
		C Berlocq	6	6					C Berlocq	79	6
		G García López	3	5				8	A Ramos	67	4
	8	A Ramos	6	7																		1/WC	R Nadal	6	62	6
																						LL	M Alund	3	77	1
								4	J Chardy	4	6	65
	WC	R Mello	4	4				LL	M Alund	6	4	77
	LL	M Alund	6	6											LL	M Alund	7	77
		D Gimeno Traver	3	6	66											F Volandri	5	65
		F Volandri	6	3	78				F Volandri	6	6
	Q	G Clezar	64	7	61			5	T Bellucci	3	2
	5	T Bellucci	77	5	77

	First round							Second round							Quarterfinals							Semifinals
	7	P Andújar	6	77
		S Giraldo	4	65				7	P Andújar	5	2
		P Lorenzi	4	4					A Montañés	7	6
		A Montañés	6	6												A Montañés	4	4
	WC	T Robredo	2	4												S Bolelli	6	6
		S Bolelli	6	6					S Bolelli	7	6
								3	J Mónaco	5	2
																							S Bolelli	3	5
	6	F Fognini	66	6	1																		D Nalbandian	6	7
		G Pella	78	1	6				G Pella	4	2
		D Nalbandian	7	5	6				D Nalbandian	6	6
	Q	J Aguilar	5	7	3											D Nalbandian	77	3	77
		H Zeballos	77	0	0r										2	N Almagro	65	6	63
	Q	P Capdeville	65	6	3			Q	P Capdeville	4	77	2
								2	N Almagro	6	63	6

1. Martín Alund

	First round							Second round							Qualifying competition
	1	João Sousa	6	63	2
		Alejandro González	4	77	6
									Alejandro González	4	7	4
									Guilherme Clezar	6	5	6
		Augusto Laranja	3	4
		Guilherme Clezar	6	6
																Guilherme Clezar	6	6
																Julio César Campozano	3	4
		Julio César Campozano	7	3	6
		Dušan Lajović	5	6	4
									Julio César Campozano	6	78
								5	Gastão Elias	2	66
	WC	Bruno Sant'Anna	1	2
	5	Gastão Elias	6	6

	First round							Second round							Qualifying competition
	2	Martín Alund	77	4	6
		Facundo Bagnis	65	6	2
								2	Martín Alund	6	6
									Marco Trungelliti	2	1
		Marco Trungelliti	6	6
		Sergio Gutiérrez Ferrol	3	1
															2	Martín Alund	6	66	65
																Jorge Aguilar	3	78	77
		Jorge Aguilar	6	6
		Ricardo Hocevar	4	3
									Jorge Aguilar	6	62	6
								6	Thiago Alves	2	77	4
	WC	Thiago Monteiro	64	2
	6	Thiago Alves	77	6

	First round							Second round							Qualifying competition
	3	Rogério Dutra da Silva	6	6
		Agustín Velotti	4	3
								3	Rogério Dutra da Silva	5	66
									Javier Martí	7	78
		Javier Martí	77	7
		Frederico Gil	65	5
																Javier Martí	4	4
															7	João Souza	6	6
		Gianluca Naso	4	6	6
		Facundo Argüello	6	3	4
									Gianluca Naso	65	6	3
								7	João Souza	77	3	6
		Dustin Brown	61	3
	7	João Souza	77	6

	First round							Second round							Qualifying competition
	4	Federico Delbonis	6	3	3
		Teymuraz Gabashvili	2	6	6
									Teymuraz Gabashvili	4	3
								PR	Julian Reister	6	6
	WC	Pedro Zerbini	79	4	4
	PR	Julian Reister	67	6	6
															PR	Julian Reister	1	3
															8	Paul Capdeville	6	6
		Guido Andreozzi	7	6
	WC	Fabiano de Paula	5	2
									Guido Andreozzi	3	6	2
								8	Paul Capdeville	6	1	6
		Steven Diez	3	2
	8	Paul Capdeville	6	6

• Main Draw
• Qualifying Draw