The African Cup of Champions Clubs 1966 was the 2nd edition of the annual international club football competition held in the CAF region (Africa), the African Cup of Champions Clubs. It determined that year's club champion of association football in Africa.

The tournament was played by 13 teams, with the winner of the previous edition (Oryx Douala) given a bye into the semi-finals. The structure of the tournament was a knock-out tournament with ties played home and away. Stade d'Abidjan from Côte d'Ivoire won the final, and became CAF club champion for the first time.

	First Round							Quarter-finals							Semi-finals							Final
															Oryx Douala		2	2	4
	Invincible Eleven		2	0	2										Real Bamako		4	3	7
	Real Bamako		3	6	9			Real Bamako		2	3	5
	Conakry I1		3	3	w/o			Conakry I		1	2	3
	US Gorée		0	0																		Real Bamako		3	1	4
	Ethio-Cement		1	0	1																	Stade d'Abidjan (a.e.t.)		1	4	5
	Al-Hilal		4	6	10			Al-Hilal		6	4	10
	Diables Noirs		1	2	3			Diables Noirs		1	1	2
	AS Dragons		2	0	2										Al-Hilal		1	2	3
	Étoile Filante (Lomé)		0	0	0										Stade d'Abidjan		0	4	4
	Asante Kotoko		3	3	6			Asante Kotoko		0	2	2
	Étoile Filante		2	1	3			Stade d'Abidjan		1	2	3
	Stade d'Abidjan		0	4	4

¹ US Gorée withdrew.

Team 1	Agg.Tooltip Aggregate score	Team 2	1st leg	2nd leg
Conakry I	w/o1	US Gorée	—	—
Diables Noirs	3–2	AS Dragons	1–2	2–0
Ethio-Cement	1–10	Al-Hilal	1–4	0–6
Étoile Filante (Lomé)	0–6	Asante Kotoko	0–3	0–3
Étoile Filante	3–4	Stade d'Abidjan	2–0	1–4
Invincible Eleven	2–9	Real Bamako	2–3	0–6
Oryx Douala	bye

¹ US Gorée withdrew.

Team 1	Agg.Tooltip Aggregate score	Team 2	1st leg	2nd leg
Al-Hilal	10–2	Diables Noirs	6–1	4–1
Asante Kotoko	2–3	Stade d'Abidjan	0–1	2–2
Real Bamako	5–3	Conakry I	2–1	3–2
Oryx Douala	bye

Team 1	Agg.Tooltip Aggregate score	Team 2	1st leg	2nd leg
Al-Hilal	3–4	Stade d'Abidjan	1–0	2–4
Oryx Douala	4–7	Real Bamako	2–4	2–3

11 December 1966

--:-- UTC+0

Real Bamako	3–1	Stade d'Abidjan
Kéïta 57' (pen.), ?' Nani 77'		Peters 1'

Stade Omnisports, Bamako

Attendance: 30 000

25 December 1966

--:-- UTC+0

Stade d'Abidjan	4–1 (a.e.t.)	Real Bamako
Déhi 15', 26' Peters 75' Bléziri 117'		Ballani ?'

Stade Félix Houphouët-Boigny, Abidjan

Attendance: 40 000

Stade d'Abidjan won 5–4 on aggregate.

1966 African Cup of Champions Clubs Stade d'Abidjan First Title

The top scorers from the 1966 African Cup of Champions Clubs are as follows:

Rank	Name	Team	Goals
1	Salif Kéïta	Real Bamako	14
2	Jaxa	Al-Hilal	7
3	Mostafa Shawish	Al-Hilal	5
4	Adama Haidara	Real Bamako	4
5	Samuel Mbappé Léppé	Oryx Douala	3
	Sidig Mohamed Ahmed	Al-Hilal	3
7	Bistouri	Diables Noirs	2
	Henri Ahibo	Stade d'Abidjan	2
	Maurice Déhi	Stade d'Abidjan	2
	Idrissa Kante	Real Bamako	2
	Abdel Mahmoud Ibrahim	Al-Hilal	2

• African Cup of Champions results at Rec.Sport.Soccer Statistics Foundation