Mother Mary was a first-century Jewish woman of Nazareth, the wife of Joseph and the mother of Jesus.

Mother Mary may also refer to:

• Maria Skobtsova (1891–1945), widely known as Mother Maria/Mary, a Russian Orthodox noblewoman and saint
• Mother Mary (1983 film), a Soviet biopic
• Mother Mary (upcoming film), an upcoming American epic melodrama film
• "Mother Mary" (song), a 2008 song by Foxboro Hot Tubs
• "Mother Mary", a song by Julian Lennon from the 1989 album Mr. Jordan
• "Mother Mary", a song by Rihanna from the 2012 album Unapologetic