The 2023 LTP Men's Open was a professional tennis tournament played on hardcourts. It was the second edition of the tournament which was part of the 2023 ATP Challenger Tour. It took place in Charleston, United States between September 25 and October 1, 2023.

Country	Player	Rank1	Seed
FRA	Enzo Couacaud	178	1
ECU	Emilio Gómez	187	2
CAN	Vasek Pospisil	188	3
USA	Tennys Sandgren	197	4
CAN	Alexis Galarneau	202	5
AUS	Adam Walton	204	6
USA	Denis Kudla	205	7
SUI	Alexander Ritschard	212	8

• ¹ Rankings are as of 18 September 2023.^[1]

The following players received wildcards into the singles main draw:

• Oliver Crawford
• Garrett Johns
• Toby Kodat

The following player received entry into the singles main draw using a protected ranking:

• Christian Harrison

The following players received entry from the qualifying draw:

• Stefan Dostanic
• Ernesto Escobedo
• August Holmgren
• Strong Kirchheimer
• Thai-Son Kwiatkowski
• Aidan Mayo

The following player received entry as a lucky loser:

• Skander Mansouri

• Abdullah Shelbayh def. Oliver Crawford 6–2, 6–7^(5–7), 6–3.

• Luke Johnson / Skander Mansouri def. Nicholas Bybel / Oliver Crawford 6–4, 6–4.