Two-time defending champion Rafael Nadal defeated Guillermo Cañas in the final, 6–3, 6–4 to win the singles tennis title at the 2007 Barcelona Open.^[1][2][3]

With the win, Nadal reached his third consecutive title at this tournament, sharing the record with Mats Wilander who won at the 1982, 1983 and 1984 editions.^[4]

The first eight seeds received a bye into the second round.

• WC – Wildcard
• Q – Qualifier
• LL – Lucky loser

	Quarterfinals							Semifinals							Finals
	1	Rafael Nadal	6	7
		Potito Starace	2	5
								1	Rafael Nadal	7	6
								5	David Ferrer	5	1
	4	David Nalbandian	65	2
	5	David Ferrer	77	6
															1	Rafael Nadal	6	6
															12	Guillermo Cañas	3	4
		Óscar Hernández	0	3
	15	Agustín Calleri	6	6
								15	Agustín Calleri	61	77	2
								12	Guillermo Cañas	77	65	6
	12	Guillermo Cañas	w/o
	2	Nikolay Davydenko

	First round							Second round							Third round							Quarterfinals
								1	Nadal	6	6
		Sanguinetti	2	4					Vliegen	1	2
		Vliegen	6	6											1	Nadal	6	6
		Lee	3	3												Johansson	1	4
		Johansson	6	6					Johansson	77	77
		Gaudio	1	0				13	Söderling	64	62
	13	Söderling	6	6																		1	Nadal	6	7
	11	Safin	4	65																			Starace	2	5
		Bolelli	6	77					Bolelli	4	3
		Starace	6	6					Starace	6	6
		Querrey	4	4												Starace	6	712
		Gabashvili	3	6	1										8	Chela	4	610
		Spadea	6	3	6				Spadea	3	3
								8	Chela	6	6

	First round							Second round							Third round							Quarterfinals
								4	Nalbandian	6	6
		Martín	6	6					Martín	2	0
		Falla	1	4											4	Nalbandian	6	6
	Q	Dustov	4	6	0										16	Moyà	4	3
	WC	Mantilla	6	1	6			WC	Mantilla	6	3	4
	WC	Granollers Pujol	2	4				16	Moyà	3	6	6
	16	Moyà	6	6																		4	Nalbandian	65	2
	10	Štěpánek	6	3	4																	5	Ferrer	77	6
		Pavel	4	6	6				Pavel	3	6	2
	Q	Pašanski	4					Q	Pašanski	6	4	6
		Berlocq	0r												Q	Pašanski	2	5
	WC	Vicente	3	78	3										5	Ferrer	6	7
		Goldstein	6	66	6				Goldstein	0	0
								5	Ferrer	6	6

	First round							Second round							Third round							Quarterfinals
								6	Nieminen	6	7
		Seppi	62	7	6				Seppi	4	5
		Karlović	77	5	3										6	Nieminen	1	78	3
		Becker	77	6											12	Hernández	6	66	6
		Kunitsyn	62	4					Becker	1	64
		Hernández	6	6					Hernández	6	77
	9	Tursunov	4	4																			Hernández	0	3
	15	Calleri	7	5	6																	15	Calleri	6	6
	WC	López	5	7	3			15	Calleri	6	6
		Galvani	78	2	61			Q	Lorenzi	2	2
	Q	Lorenzi	66	6	77										15	Calleri	6	2	6
		García López	5	3											3	Robredo	4	6	3
		López	7	6					López	2	2
								3	Robredo	6	6

	First round							Second round							Third round							Quarterfinals
								7	Ferrero	1r
	Q	Andújar	6	6				Q	Andújar	2
	WC	Salvà	4	0											Q	Andújar	5	3
		Vaněk	6	3											12	Cañas	7	6
	Q	Marín	0	2r					Vaněk	1	1
		Mirnyi	2	64				12	Cañas	6	6
	12	Cañas	6	77																		12	Cañas	w/o
	14	Almagro	6	6																		2	Davydenko
	Q	Fognini	3	2				14	Almagro	77	4	1
		Volandri	6	6					Volandri	65	6	6
		Korolev	0	4												Volandri	65	66
	Q	Schukin	6	6											2	Davydenko	77	77
		Eschauer	4	4				Q	Schukin	4	6	2
								2	Davydenko	6	3	6

	First round							Qualifying competition
	1	Iván Navarro	3	2
		Flavio Cipolla	6	6
									Flavio Cipolla	6	3	63
								8	Farrukh Dustov	4	6	77
		Julien Jeanpierre	5	2
	8	Farrukh Dustov	7	6

	First round							Qualifying competition
	2	Ilija Bozoljac	4	0r
		Ivo Klec	6	0
									Ivo Klec	4	6	4
									Yuri Schukin	6	4	6
		Yuri Schukin	6	0
	13	Michał Przysiężny	2	0r

	First round							Qualifying competition
	3	Albert Portas	7	4	6
	WC	Sergey Bubka	5	6	3
								3	Albert Portas	5	3
								14	Fabio Fognini	7	6
		Rainer Eitzinger	2	5
	14	Fabio Fognini	6	7

	First round							Qualifying competition
	4	Roko Karanušić	6	6
	WC	Javier Garrapiz-Borderías	0	1
								4	Roko Karanušić	3	4
								12	Paolo Lorenzi	6	6
		Alun Jones	1	61
	12	Paolo Lorenzi	6	77

	First round							Qualifying competition
	5	Gorka Fraile	3	4
		Boris Pašanski	6	6
									Boris Pašanski	6	4	6
									Marc Fornell Mestres	3	6	3
		Marc Fornell Mestres	6	6
	11	George Bastl	1	3

	First round							Qualifying competition
	6	Denis Gremelmayr	5	6	6
	WC	Albert Ramos Viñolas	7	4	2
								6	Denis Gremelmayr	2	6	1
								Alt	Juan Antonio Marín	6	3	6
	Alt	Juan Antonio Marín	6	6
	9	Lukáš Lacko	4	3

	First round							Qualifying competition
	7	Nathan Healey	7	6
	WC	Ignacio Coll Riudavets	5	3
								7	Nathan Healey	4	3
								10	Pablo Andújar	6	6
		Simone Vagnozzi	65	6	4
	10	Pablo Andújar	77	3	6

• Singles draw
• Singles qualification draw
• ITF tournament profile