Spruce Grove is a city in Alberta, Canada.
Spruce Grove may also refer to:
- Canada
- Edmonton—Spruce Grove, federal electoral district in Alberta
- Spruce Grove-Sturgeon-St. Albert, provincial electoral district in Alberta
- United States
- Spruce Grove, California, former name of Harris, California
- Spruce Grove Township, Becker County, Minnesota, township in Minnesota
- Spruce Grove Township, Beltrami County, Minnesota, township in Minnesota
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