Saint Jerome is a Christian church father, best known for translating the Bible into Latin.

Saint Jerome may also refer to:

• Jerome of Pavia (fl. 778 – c. 787), Bishop of Pavia
• Jerome Emiliani (1486–1537), Italian humanitarian and founder of the Somaschi Fathers
• Jerome Hermosilla, one of the Vietnamese Martyrs

• Saint-Jérôme, Quebec, a suburb of Montreal, Canada
  • Saint-Jérôme (electoral district)
  • Roman Catholic Diocese of Saint-Jérôme
  • Saint-Jérôme line, a commuter railway line
    • Saint-Jérôme (AMT), a bus and train station
• Boyeux-Saint-Jérôme, a commune in the Ain department, France

• Saint Jerome High School, a former school in Holyoke, Massachusetts, the United States
• Saint Jerome's Academy, a school in Bagabag, Nueva Vizcaya, the Philippines
• St. Jerome's University, a university in Waterloo, Ontario, Canada

• Saint Jerome (El Greco), a painting of 1609 by El Greco
• Saint Jerome (Guercino), a painting of c. 1640–1650 by Guercino
• Saint Jerome (Ribera) a painting of 1651 by Jusepe de Ribera
• Saint Jerome (Stom), a painting of c. 1635 by Matthias Stom
• Saint Jerome (Master Theodoric), a painting of c. 1370 by Master Theodoric
• Saint Jerome (Tura), a painting of c. 1470 by Cosmè Tura
• "Saint Jerome", a song by Jason Schwartzman on the 2009 album Davy

• St. Jerome Church (disambiguation)
• San Geronimo (disambiguation)
• San Girolamo (disambiguation)
• San Jerónimo (disambiguation)
• All pages with titles containing Saint Jerome