Ring finger protein 167 is a protein that in humans is encoded by the RNF167 gene.[5]
Function
RNF167 is an E3 ubiquitin ligase that interacts with TSSC5 (SLC22A18; MIM 602631) and, together with UBCH6 (UBE2E1; MIM 602916), facilitates TSSC5 polyubiquitylation.[6]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000108523 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040746 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Ring finger protein 167". Retrieved 2018-09-10.
- ^ Yamada, H. Y.; Gorbsky, G. J. (March 2006). "Tumor suppressor candidate TSSC5 is regulated by UbcH6 and a novel ubiquitin ligase RING105". Oncogene. 25 (9): 1330–1339. doi:10.1038/sj.onc.1209167. ISSN 1476-5594. PMC 2713668.
Further reading
- Lussier MP, Herring BE, Nasu-Nishimura Y, Neutzner A, Karbowski M, Youle RJ, Nicoll RA, Roche KW (November 2012). "Ubiquitin ligase RNF167 regulates AMPA receptor-mediated synaptic transmission". Proc. Natl. Acad. Sci. U.S.A. 109 (47): 19426–31. Bibcode:2012PNAS..10919426L. doi:10.1073/pnas.1217477109. PMC 3511152. PMID 23129617.
- Yamazaki Y, Schönherr C, Varshney GK, Dogru M, Hallberg B, Palmer RH (February 2013). "Goliath family E3 ligases regulate the recycling endosome pathway via VAMP3 ubiquitylation". EMBO J. 32 (4): 524–37. doi:10.1038/emboj.2013.1. PMC 3579141. PMID 23353890.
- van Dijk JR, Yamazaki Y, Palmer RH (April 2014). "Tumour-associated mutations of PA-TM-RING ubiquitin ligases RNF167/RNF13 identify the PA domain as a determinant for endosomal localization". Biochem. J. 459 (1): 27–36. doi:10.1042/BJ20131067. PMID 24387786.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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