Morales is a Spanish surname. Notable people with the surname include:

• Alfredo Morales (born 1990), American footballer
• Alvaro Morales (disambiguation), several people
• Amado Morales (born 1947), Puerto Rican javelin thrower
• Bartolomé Morales (1737–?), Spanish officer and Florida colonial official
• Campo Elías Delgado Morales (1934–1986), Colombian spree killer
• Carlos Adrián Morales, Mexican football (soccer) player
• Carlos Luis Morales, Ecuadorian football (soccer) goalkeeper
• Carlos Morales Santos, Paraguayan football (soccer) player
• Carlos Morales Troncoso (1940-2014), Dominican politician, former foreign minister
• Carlos Morales (American soccer) (born 1982), Puerto Rican football (soccer) player
• Christina Morales, American politician
• Cristina Morales (born 1993), Spanish kickboxer
• Cristóbal de Morales (c. 1500 – 1553), Spanish composer
• Dan Morales (born 1956), American politician from Texas
• Daniel Morales (footballer) (born 1975), Brazilian footballer
• Daniel Morales (swimmer) (born 1977), Spanish former swimmer
• David Morales (musician) (born 1961), New York-based American DJ and music producer
• David Sánchez Morales (1925–1978), American CIA operative
• Dianne Morales (born 1967), American non-profit executive and political candidate
• Eduardo Morales Miranda, Chilean physician and founder of Universidad Austral de Chile
• Enrique Martín Morales, known as Ricky Martin, Grammy Award winning Puerto Rican pop singer
• Erik Morales (born 1976), Mexican professional boxer
• Esai Morales (born 1962), Puerto Rican actor
• Evo Morales (born 1959), President of Bolivia
• Fabio de Jesús Morales Grisales (1934–2025), Colombian Roman Catholic bishop
• Fernando Morales (volleyball) (born 1982), Puerto Rican volleyball player
• Florencio Morales Ramos (1915–1989), Puerto Rican singer, trovador and composer
• Francisco Morales (disambiguation), several people
• Franco Morales (born 1992), Chilean basketball player
• Frank Morales (born 1949), New York City-based American priest and journalist
• Franklin Morales (born 1986), Venezuelan baseball player
• Franklin E. Morales (1884–1962), American diplomat
• Guillem Morales (born 1973), Spanish filmmaker
• Jacobo Morales (born 1934), Puerto Rican actor
• Javier Morales (born 1980), Argentine football (soccer) player
• Jimmy Morales (born 1969), President of Guatemala (2016–2020)
• José Morales (designated hitter) (born 1944), American baseball player
• José Luis Morales (born 1973), Spanish football player
• José Luis Morales (born 1987), Spanish football player
• Juan Bautista Morales (c. 1597–1664), Spanish Dominican missionary
• Kendrys Morales (born 1983), Cuban baseball player
• Leonardo Morales (Scouting), Costa Rican scout leader
• Luis Morales (athlete) (born 1964), Puerto Rican track and field sprinter
• Makisig Morales (born 1996), Filipino former actor
• Manolo Rivera Morales (1934–1996), Puerto Rican sportscaster
• Manuel Morales (basketball) (born 1987), Peruvian basketball player
• Marco Morales (American football), American football player
• María Antonia Morales (1931–2024), Chilean judge and lawyer
• Mario Morales (born 1960), Puerto Rican basketball player
• Mark Morales (aka Prince Markie Dee) (1968–2021), American dance music producer
• Memo Morales (1937–2017), Venezuelan singer
• Mikoy Morales (born 1993), Filipino actor
• Natalie Morales (actress), American actress
• Natalie Morales (journalist), American journalist for NBC
• Pablo Morales (born 1962) American Olympic swimmer, Gold and Silver medalist
• Pablo Morales Pérez (1905–1969), Venezuelan baseball executive and promoter
• Pedro Morales (1942–2019), Puerto Rican professional wrestler
• Pedro Morales Flores (born 1985), Chilean football player
• Rags Morales, American comic book artist
• Ramón Morales (born 1975), Mexican professional footballer
• Dr. Ramón Villeda Morales (1908–1971), President of Honduras
• Rebecca Jo Morales (born 1962), American artist
• Ricardo Arjona Morales, Guatemalan song writer, music producer, poet, singer
• Ricardo Morales (born 1972), American musician
• Rodolfo Morales (1925–2001), Mexican artist
• Sylvestro "Pedro" Morales (18??–1???), Mexican bandit
• Vicky Morales (born 1969), Filipino broadcast journalist and television presenter
• Vina Morales (born 1975 as Sharon Garcia Magdayao), Filipino singer and actress
• Virgilio Morales Díaz, Cuban Boy Scout leader

• Cristóbal de Morales (c. 1500 – 1553), Spanish composer
• Luis de Morales (c. 1510 – 1586), Spanish painter

• Gerardo Machado y Morales (1871–1939), Cuban politician

• Morales, in the television series The Walking Dead
• Jim Moralés, in Code Lyoko (voiced by David Gasman)
• Enrique Morales, in the HBO series Oz
• Lt. Morales, the combat medic, a playable character in the video game Heroes of the Storm
• Ramón Morales, in the 2019 film Scary Stories to Tell in the Dark
• Miles Morales, Spider-Man in the Ultimate Comics: Spider-Man comic book series
• Charlotte Morales, Spider-Girl, in the Spider-Gwen comic book series
• Diana Morales, character in the musical A Chorus Line