María Luisa ("Magüi") Serna Barrera (Spanish pronunciation: [maˈɾi.a ˈlwisa ˈmaɣwi ˈseɾna βaˈreɾa];^[a] born 1 March 1979) is a former tennis player from Spain.

She started competing on the ITF Circuit as from 1993, and joined the WTA Tour in 1996. On 12 January 2004, she reached her career-high singles ranking of world No. 19.

Serna produced an upset by defeating Justine Henin in the 2001 Scottsdale tournament, 7–6, 7–6.

Result	W-L	Date	Tournament	Surface	Opponent	Score
Loss	0–1	Apr 2001	Porto, Portugal	Clay	Arantxa Sánchez Vicario	3–6, 1–6
Loss	0–2	Jun 2001	Eastbourne, UK	Grass	Lindsay Davenport	2–6, 0–6
Loss	0–3	Apr 2002	Porto, Portugal	Clay	Ángeles Montolio	1–6, 6–2, 5–7
Win	1–3	Apr 2002	Estoril, Portugal	Clay	Anca Barna	6–4, 6–2
Win	2–3	Apr 2003	Estoril, Portugal	Clay	Julia Schruff	6–4, 6–1
Win	3–3	Apr 2003	Budapest, Hungary	Clay	Alicia Molik	3–6, 7–5, 6–4

Result	No.	Date	Tournament	Surface	Partner	Opponents	Score
Loss	0–1	May 2000	Rome, Italy	Clay	Arantxa Sánchez Vicario	Lisa Raymond Rennae Stubbs	3–6, 6–4, 2–6
Win	1–1	Jul 2001	Knokke-Heist, Belgium	Clay	Virginia Ruano Pascual	Ruxandra Dragomir Andreea Vanc	6–4, 6–3
Loss	1–2	Apr 2002	Porto, Portugal	Clay	Kristie Boogert	Cara Black Irina Selyutina	6–7(6–8), 4–6
Loss	1–3	Jun 2003	Eastbourne, United Kingdom	Grass	Jennifer Capriati	Lindsay Davenport Lisa Raymond	3–6, 2–6
Loss	1–4	Aug 2003	New Haven, United States	Hard	Alicia Molik	Virginia Ruano Pascual Paola Suárez	6–7(6–8), 3–6
Win	2–4	Jun 2004	Eastbourne, United Kingdom	Grass	Alicia Molik	Svetlana Kuznetsova Elena Likhovtseva	6–4, 6–4

Outcome	No.	Date	Tournament	Surface	Opponent	Score
Winner	1.	3 April 1994	Gaborone, Botswana	Hard	Shirli-Ann Siddall	6–3, 6–4
Winner	2.	10 April 1994	Harare, Zimbabwe	Hard	Shirli-Ann Siddall	6–4, 6–2
Runner-up	1.	4 July 1994	Felixstowe, United Kingdom	Grass	Tatiana Panova	7–5, 3–6, 3–6
Runner-up	2.	19 March 1995	Zaragoza, Spain	Clay	Virginia Ruano Pascual	6–2, 6–7, 2–6
Runner-up	3.	14 August 1995	Koksijde, Belgium	Clay	Sarah Pitkowski	1–6, 3–6
Runner-up	4.	21 August 1995	Brussels, Belgium	Clay	Conchita Martínez Granados	0–6, 4–6
Winner	3.	3 December 1995	Mallorca, Spain	Clay (i)	Kira Nagy	6–4, 6–3
Winner	4.	28 July 1996	Valladolid, Spain	Hard	Hila Rosen	6–3, 6–1
Winner	5.	18 August 1996	Wahlscheid, Germany	Clay	Alena Vašková	6–2, 6–3
Winner	6.	25 August 1996	Athens, Greece	Clay	Mariana Díaz Oliva	5–7, 6–3, 6–2
Runner-up	5.	11 March 2006	Telde, Spain	Clay	Aravane Rezaï	4–6, 1–6

Outcome	No.	Date	Tournament	Surface	Partner	Opponents	Score
Runner-up	1.	27 March 1994	Nairobi, Kenya	Hard	Sybille Seyfried	Cara Black Nannie de Villiers	2–6, 2–6
Winner	1.	3 April 1994	Gaborone, Botswana	Hard	Amanda Hopmans	Evelyn Fauth Radka Surová	6–3, 6–1

• Magüi Serna at the Women's Tennis Association
• Magüi Serna at the International Tennis Federation
• Magüi Serna at the Billie Jean King Cup (archived)