The following highways are numbered 346:

Avenel-Nagambie Road

• Manitoba Provincial Road 346
• Newfoundland and Labrador Route 346
• Quebec Route 346

• Japan National Route 346

• Georgia State Route 346 (former)
• Iowa Highway 346
• Kentucky Route 346
• Louisiana Highway 346
• Maryland Route 346
• New York:
  • New York State Route 346
  • County Route 346 (Erie County, New York)
  • County Route 346 (Wayne County, New York)
• Pennsylvania Route 346
• Puerto Rico Highway 346
• South Carolina Highway 346
• Tennessee State Route 346
• Texas:
  • Texas State Highway 346 (former)
  • Farm to Market Road 346
• Vermont Route 346
• Virginia State Route 346