Kallidin is a bioactive kinin peptide formed in response to injury from kininogen precursors through the action of kallikreins.[1]

Kallidin is a decapeptide whose sequence is H-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH. It can be converted to bradykinin by the aminopeptidase enzyme.[citation needed]

It can be a substrate for carboxypeptidase M and N.[2]

Kallidin is identical to bradykinin with an additional lysine residue added at the N-terminal end and signals through the bradykinin receptor.[citation needed]

References

  1. ^ Campbell, Duncan John (2013). "Bradykinin Peptides". Handbook of Biologically Active Peptides. pp. 1386–1393. doi:10.1016/B978-0-12-385095-9.00188-3. ISBN 978-0-12-385095-9.
  2. ^ Herwald, Heiko; Müller-Esterl, Werner; Renné, Thomas (2008). "Kinins". Encyclopedia of Molecular Pharmacology. pp. 673–676. doi:10.1007/978-3-540-38918-7_86. ISBN 978-3-540-38916-3.


Allikas: https://en.wikipedia.org/wiki/Kallidin
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