Daphne is a water nymph in Greek mythology.

Daphne may also refer to:

• Daphne Palace, Constantinople, Turkey
• Daphni Monastery, near Athens
• Daphne Island, a river island in Alberta, Canada
• Daphne Major, in the Galápagos Islands
• Daphne, Alabama, a city in the United States
• A former suburb of the ancient city of Antioch, today Harbiye, Antakya, Turkey
• Constantiana Daphne, Byzantine fortification on Danube
• Daphne (Mount Athos), Greece, likely site of ancient Cleonae
• Daphne (Thrace), a town of ancient Thrace, now in Turkey
• Rablah / Riblah, formerly also known by the name Daphne

• HMS Daphne, Royal Navy ships
• Daphné-class submarine, a French Navy class
  • French submarine Daphné (S641), lead submarine of the class
• Daphne-class Seaward Defence Craft, Royal Danish Navy
• Daphne (brig), a ship that was wrecked in 1819
• SS Daphne (1883), a ship which sank disastrously in 1883
• Princess Daphne (ship), a cruise ship operated by Costa Cruises (1979–1997)

• Daphne (given name), including a list of persons and fictional characters with the given name
• Daphne (singer), Cameroonian singer Daphne Njie Efundem (born 1986)

• "Daphne", on several Django Reinhardt albums, such as Djangology; written in 1937
• "Daphne", from the 2002 1 Giant Leap album 1 Giant Leap
• "Daphne", from the 2011 Lia Ices album Grown Unknown
• "Daphne", by from British band Squeeze their 1995 album Ridiculous
• "Daphne", by Bat for Lashes from the album The Haunted Man
• "Daphne", from the 2001 John Paul Jones album The Thunderthief

• Daphne (opera), a 1938 opera by Richard Strauss based on the myth and legend of the nymph
• Daphne (2017 film), a British drama film
• Daphne (2007 film), a British biographical drama film
• Daphne (comedy), a British comedy trio
• DAPHNE (emulator), an emulator of Laserdisc arcade games
• Daphne (plant), a genus of shrubs
• Détecteur à Grande Acceptance pour la Physique Photonucléaire Expérimentale, a particle detector
• DAPHNE project, a European Commission-funded project under FP7 research funding
• Ethinylestradiol/cyproterone acetate, a birth control pill

• Daffney (born 1975), American professional wrestler
• Dafney, a surname
• Daphnia, small planktonic crustaceans
• Plant genus names:
  • Daphnandra
  • Daphnidium, synonym of Lindera
  • Daphniphyllum
  • Daphnopsis
• Dafne (disambiguation)
• Dafni (disambiguation)
• Dafny (programming language)
• Daphne Laureola