Constantina is the feminine form of Constantine. It may refer to:
- Constantina, a Byzantine saint, the eldest daughter of Roman Emperor Constantine I and his second wife Fausta
- Constantina (empress), Byzantine empress, daughter of Tiberius II and wife of Maurice
- Constantina, Brazil, a Brazilian municipality in Rio Grande do Sul
- Constantina, Seville, a Spanish municipality in the province of Seville.
- Constantina (Osrhoene), a Roman/Byzantine city in northern Mesopotamia
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