Clarence is a masculine given name. Notable people with the name include:

• Clarence 13X (1928–1969), American religious leader and the founder of the Five-Percent Nation
• Clarence Acuña (born 1975), Chilean professional footballer
• Clarence Applegran (1893–1960), American football player and basketball coach
• Clarence Ashley (1895–1967), American musician and singer
• Clarence Avant (1931–2023), American music executive and film producer
• Clarence Albert Bacote (1906–1981), American historian and activist
• Clarence Bailey (1963–2006), American football player
• Clarence Bamberger (1886–1984), American mining executive, politician and philanthropist
• Clarence Barlow (1945–2023), British composer
• Clarence W. Barron (1855–1928), American financial editor and publisher who founded Barron's Magazine
• Clarence Beavers (1921–2017), American United States Army sergeant and paratrooper
• Clarence Birdseye (1886–1956), pioneer of frozen food
• Clarence Brown (disambiguation), several people
• Clarence Sinclair Bull (1896–June 8, 1979), American portrait photographer
• Clarence Burton (1882–1933), American actor
• Clarence G. Burton (1886–1982), American politician
• Clarence M. Burton (1853–1932), American lawyer, businessman, historian and philanthropist
• Clarence Campbell (1905–1984), Canadian ice hockey executive, referee, and soldier
• Clarence Thomas Campbell (1843–1922), Canadian physician, historian and politician
• Clarence Cannon (1879–1964), American politician
• Clarence Carnes (1927–1988), American fugitive
• Clarence Carter (born 1936), blind US soul singer and musician
• Clarence Holbrook Carter (1904–2000), US painter
• Clarence Clemons (1942–2011), American musician, saxophonist for the E Street Band
• Clarence Cummings (born 2000), American Olympic weightlifter
• Clarence Dart (1920–2012), American World War II fighter pilot and member of the Tuskegee Airmen
• Clarence Delgado (born 2004), Filipino teen actor
• Clarence DeMar (1888–1958), American marathoner
• Clarence Dill (1884–1978), American politician
• Clarence Dixon (1955–2022), American murderer
• Clarence Darrow (1857–1938), American lawyer
• Clarence Day (1874–1935), American author and cartoonist
• Clarence Dillon (1882–1979), American financier and businessman
• Clarence Ransom Edwards (1859–1931), American general
• Clarence Edwards (1933–1993), American blues musician
• Clarence Elkins (born 1963), American man who was wrongfully convicted of murder
• Clarence Fok, Hong Kong-Canadian film director and actor
• Clarence Gaines (1923–2005), American college basketball player and coach
• Clarence Gillis (1895–1960), Canadian politician
• Clarence Gilyard (1955–2022), American university professor, actor and author
• Clarence Goodson (born 1982), US footballer
• Clarence Henry (boxer) (1926–1999), American boxer
• Clarence "Frogman" Henry (born 1937), American rhythm and blues singer and pianist
• Clarence Z. Hubbell (1869–1953), American architect
• Clarence Janecek (1911–1990), NFL player
• Clarence Jey, American record producer
• Clarence Johnson (1910–1990), US aeronautical engineer
• Clarence King (1842–1901), American geologist, mountaineer, and author
• Clarence Kolster (1895–1972), American film editor
• Clarence Lam (born 1980), American politician and physician who has served in the Maryland Senate representing the 12th district since 2019
• Clarence F. Leary (1894–1918), American officer in the United States Navy during World War I
• Clarence P. LeMire (1886–1961), judge of the United States Tax Court
• Clarence Long (1908–1994), American politician
• Clarence Lung (1914–1993), American actor
• Clarence Mackay (1874–1938), American financier and philanthropist
• Clarence D. Martin (1886–1955), 11th Governor of the state of Washington
• Clarence R. Martin (1886–1972), Justice of the Indiana Supreme Court
• Clarence Edward Mathias (1876–1935), US Sergeant major, Medal of Honor recipient
• Clarence McNair (born 1977), American writer and entrepreneur
• Clarence Mitchell Jr. (1911-1984), an American civil rights activist and chief lobbyist for the NAACP for nearly 30 years
• Clarence Mitchell III (1939-2012), an American politician and son of Clarence Mitchell Jr.
• Clarence Mitchell IV (born 1962), an American radio cohost of The C4 And Bryan Nehman Show, former American politician, son of Clarence Mitchell III, and grandson of Clarence Mitchell Jr.
• Clarence Moore (disambiguation), several people
• Clarence Morley (1869–1948), American politician
• Clarence E. Mulford (1883–1956), American writer
• Clarence Nash (1904–1985), American voice actor
• Clarence Charles Newcomer (1923–2005), US District Judge of the United States District Court for the Eastern District of Pennsylvania
• Clarence Paul Oliver (1898–1991), American geneticist
• Clarence Page (born 1947), American journalist
• Clarence Perry (1872–1944), American urban planner, sociologist, author, and educator
• Clarence J. Roberts (1873–1931), Justice of the New Mexico Supreme Court
• Clarence Ryan, Australian actor
• Clarence Sasser (1947–2024), American soldier and recipient of the Medal of Honor
• Clarence Saunders (athlete), Bermudian high jumper
• Clarence Saunders (grocer), US American retailer, pioneer of supermarkets
• Clarence Scharbauer (1879–1942), American rancher
• Clarence Schmalz (1916–1981), Canadian ice hockey administrator
• Clarence Seedorf (born 1976), Dutch footballer
• Clarence Smith (disambiguation), several people
• Clarence A. Southerland (1889–1973), Chief Justice of the Delaware Supreme Court
• Clarence Stoner (1901–1994), American politician from Pennsylvania
• Clarence Swensen (1917–2009), American actor
• Clarence Thomas, Associate Justice of the Supreme Court of the United States
• Clarence L. Townes Jr. (1928–2017), American businessperson, politician, civic activist
• Clarence J. A. Turner (1893–1957), American jockey
• Clarence W. Turner (1866–1939), American lawyer and politician
• Clarence Watters (1902−1986), American organist
• Clarence N. Weems Jr., American scholar and military officer
• Clarence White (1944–1973), American guitarist and singer
• Clarence Cameron White (1880–1960), American composer
• Clarence Hudson White (1871–1925), American photographer
• Clarence Whitehill (1871–1932), American opera singer
• Clarence Wijewardena, Sri Lankan guitarist and vocalist
• Clarence Williams III (1939–2021), American actor
• Clarence Wiseman, Canadian clergy, tenth general of The Salvation Army
• Clarence Zener (1905–1993), American physicist

• Clarence Odbody, a guardian angel from the 1946 film It's a Wonderful Life
• Lumpy Rutherford, a recurring character in Leave It to Beaver, an American TV series
• Clarence Wendle, the titular character in the Cartoon Network TV show Clarence
• The title character of Clarence, a 1988 British TV series, portrayed by Ronnie Barker
• Clarence (Razor) Callahan, the main antagonist in the 2005 video game Need for Speed: Most Wanted
• Clarence, a wise and virtuous orangutan who acts as adviser to the chimpanzee leader Khan on the 2017 video game Planet of the Apes: Last Frontier.