St. Brother André Catholic High School is a Catholic secondary school in Markham, Ontario, Canada. Grades 9 to 12 are taught, with religious studies included in the curriculum. It is named after Saint André Bessette (also known as Brother André), a 20th-century Catholic religious brother in Montreal responsible for the construction of the Saint Joseph's Oratory.

Brother André is located in east-central Markham, and its feeder schools include

• St. Kateri Tekakwitha CES
• San Lorenzo Ruiz Catholic Elementary School
• St. Edward CES
• St. Joseph CES (Markham)
• St. Julia Billiart CES
• St. Justin Martyr (Markham)
• St. Patrick CES (Markham)
• St. Mark CES (Stouffville)
• St. Brigid CES (Stouffville)
• St. Brendan CES (Stouffville)

On April 28, 2010, a fire broke out at St. Brother André Catholic High School in the boys' washroom on the second floor.^[2] One person was treated for smoke inhalation and personal anxiety. Former principal Jim Nicoletti said that there was a "minor" investigation in progress by the York Regional Police.^[3]

• Steven Stamkos, professional ice hockey centre and team captain for the Tampa Bay Lightning of the National Hockey League (NHL)
• Michael Del Zotto, professional ice hockey defenseman for the Anaheim Ducks of the National Hockey League (NHL)
• Mena Massoud, actor who played Aladdin in Disney's live-action remake of Aladdin.
• Andrew Lue, former professional football player for the Montreal Alouettes of the Canadian Football League (CFL)

• 
  St. Joseph's Chapel, the school chapel of St. Brother Andre CHS in 2019, prior to the 2021 redecoration
• 
  St. Joseph's Chapel after the 2021 redecoration
• 
  St. Joseph's Chapel after the 2023 redecoration.

• Education in Ontario
• List of secondary schools in Ontario