Blankenship is a family name that may refer to:

• Beau Blankenship (born 1990), American football player
• Ben Blankenship (born 1988), American Olympic middle-distance runner
• Bill Blankenship (born 1956), American football coach and player
• Brian Blankenship (born 1963), retired professional American football player
• Cliff Blankenship (1880–1956), American baseball player
• Cooper Blankenship (1929–2015), American politician
• Don Blankenship (born 1950), former Chairman and CEO of the Massey Energy coal mining corporation
• Erin Blankenship, American statistics educator
• G. T. Blankenship (born 1928), American lawyer and politician
• Georgiana M. Blankenship (1861–1936), American pioneer and author
• Greg Blankenship (born 1954), American football player
• Homer Blankenship (1902–1974), American baseball player
• J. Richard Blankenship (born 1959), American diplomat
• Jacob Blankenship (born 1994), American pole vaulter
• Jacob Blankenship (basketball) (born 1989), Greek-American basketball player
• Josh Blankenship (born 1980), American football player and coach
• Kenny Blankenship, the name given to the character portrayed by personality Sonomanma Higashi and voiced by Christopher Darga, on MXC, the American parody/adaptation of Takeshi's Castle
• Kevin Blankenship (born 1963), American baseball player
• Kim Blankenship, American sociologist and HIV/AIDS researcher
• Lance Blankenship, (born 1963), retired Major League Baseball utility player
• Loyd Blankenship (born 1965), American computer hacker and writer
• Mark Blankenship (born 1978), writer and blogger
• Rachel Blankenship (born September 2, 1995), American soccer player
• Reed Blankenship (born 1999), American football player
• Robert E. Blankenship, American chemist
• Rodrigo Blankenship (born 1997), American football placekicker

• Ted Blankenship (1901–1945), American baseball player
• Tom Blankenship (born 1978), American bass guitarist for the band My Morning Jacket
• William Blankenship (1928–2017), American opera singer