Alcmene is mother of Heracles in Greek mythology.
Alcmene or Alkmene may also refer to:
- 82 Alkmene, an asteroid
- Alkmene (apple)
- Alkmene (opera), by Giselher Klebe
- HMS Alcmene, several ships of the British Royal Navy
- French ship Alcmène, several ships of the French Navy
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